Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Goats

    January 2022 in “ Figshare ”
    Chun Li, Cong Feng, Guangyuan Ma, Su Fu, Ming Chen, Wenguang Zhang, Jinquan Li
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    TLDR Melatonin affects different genes and pathways important for goat hair growth.
    The document presents data from a study examining gene expression patterns during the hair follicle growth cycle in goats, specifically focusing on the impact of melatonin. The data reveals that multiple signaling pathways, including the Hippo signaling pathway, Melanogenesis, Wnt signaling pathway, and pathways regulating pluripotency of stem cells, play a role in this process. Key genes identified within these pathways include FZD3, BMP2, WNT11, WNT2B, among others. These findings suggest that these pathways and genes could be crucial in understanding hair follicle growth and may be potential targets for hair growth treatments. The document, however, does not specify the number of goats used in the study.
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