Spironolactone for Treatment of Concomitant Female Pattern Hair Loss in Scarring Alopecia Patients

    April 2021 in “ Journal of Investigative Dermatology ”
    Kelly E. Flanagan, James T. Pathoulas, Christopher K. Walker, I.M. Pupo Wiss, Maryanne M. Senna
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    TLDR Spironolactone safely and effectively treats hair loss in female scarring alopecia patients.
    The study evaluated the use of spironolactone in female scarring alopecia patients with concomitant pattern hair loss. The drug was well-tolerated by most patients, with only a few reporting side effects. Patients who used spironolactone for at least 6 months showed an improvement in Sinclair score, indicating the drug's efficacy in treating hair loss in these patients. The study concludes that spironolactone is a safe and effective treatment option for female scarring alopecia patients with concomitant pattern hair loss.
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      community C’est terrible - at my wits end

      in Female  449 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community My scalp punch biopsy results🤔?

      in Female  9 upvotes 1 year ago
      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

      community Do hair follicles dies or are dormant ?

      in Finasteride/Dutasteride  92 upvotes 4 weeks ago
      Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 8 months ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

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