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    Glossary CXCR3

    receptor on immune cells guiding them to inflammation sites

    CXCR3 is a receptor found on the surface of certain immune cells, such as T cells. It plays a crucial role in directing these cells to sites of inflammation or injury by binding to specific signaling molecules called chemokines. This receptor is important in various immune responses and has been implicated in conditions like autoimmune diseases and alopecia, where the immune system mistakenly attacks the body's own tissues.

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    Research 30 of 730

    1. PD-1+CXCR5−CD4+T cells are correlated with the severity of systemic lupus erythematosus Rheumatology · 2019 · 71 citations
    2. CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata Journal of Immunology · 2016 · 64 citations
    3. Author response: Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis 2019 · 1 citations
    4. Decision letter: Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis 2019
    5. Regulatory T cells in skin utilize the Cxcr4-Cxcl12 axis to promote hair follicle regeneration Cell Reports · 2025
    6. CXCL12 inhibits hair growth through CXCR4 Biomedicine & Pharmacotherapy · 2022
    7. Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis Cancer Research · 2008 · 70 citations
    8. Preconditioning with far-infrared irradiation enhances proliferation, cell survival, and migration of rat bone marrow-derived stem cells via CXCR4-ERK pathways Scientific Reports · 2017 · 44 citations
    9. Plerixafor Engages β-Arrestin-Dependent CXCR4 Signaling to Promote Melanogenesis via β-Catenin-MITF Activation Current Issues in Molecular Biology · 2026
    10. Plerixafor Biases CXCR4 Signaling Through β-Arrestin to Promote Melanogenesis via β-Catenin–MITF Activation Preprints.org · 2026
    11. 744 Role of Sdf1-Cxcr4 signaling in mouse appendage regeneration Journal of Investigative Dermatology · 2016
    12. Insights into the context-dependent immunological roles of the CXCL12–CXCR4 axis in alopecia Frontiers in Immunology · 2026
    13. Type 1 interferon signature in the scalp lesions of alopecia areata British Journal of Dermatology · 2010 · 52 citations
    14. Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development 2012 · 48 citations
    15. Increased Circulating CXCL10 in Non-Segmental Vitiligo Concomitant with Autoimmune Thyroid Disease and Alopecia Areata Annals of Dermatology · 2019 · 17 citations
    16. Antroquinonol Exerts Immunosuppressive Effect on CD8<sup>+</sup> T Cell Proliferation and Activation to Resist Depigmentation Induced by H<sub>2</sub>O<sub>2</sub> Oxidative medicine and cellular longevity · 2017 · 11 citations
    17. Alopecia areata possibly induced by autoimmune reaction in a patient with human T‐cell lymphotropic virus‐1‐associated myelopathy The Journal of Dermatology · 2013 · 6 citations
    18. Th1 Chemokine CXCL10 and Alopecia Areata: The Possible Target for the Treatment of Alopecia Areata Journal of Clinical & Cellular Immunology · 2016 · 3 citations
    19. Cross-species comparative spatial transcriptomics of hair follicle-T cell interactions identifies conserved drivers of cutaneous lupus erythematosus skin disease and associated hair loss Nature Communications · 2026
    20. Comprehensive transcriptome profiling between balding and non-balding scalp of female pattern hair loss in Asian Archives of Dermatological Research · 2024
    21. Comprehensive transcriptome profiling between balding and non-balding scalp of Female pattern hair loss in Asian Research Square (Research Square) · 2024
    22. SnapshotDx Quiz: February 2018 Journal of Investigative Dermatology · 2018
    23. 0034 Cross-species insights into hair follicle-T cell interactions in discoid lupus erythematosus: A comparison of human, canine and mouse models using spatial transcriptomics Journal of Investigative Dermatology · 2025
    24. Comparative spatial transcriptomics of hair follicle-T cell interactions in mouse, dog and human reveals conserved drivers of primary cicatricial alopecia bioRxiv (Cold Spring Harbor Laboratory) · 2025
    25. Scarless wound healing: finding the right cells and signals Cell and Tissue Research · 2016 · 132 citations
    26. The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles Differentiation · 2009 · 57 citations
    27. Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin Stem Cells · 2013 · 43 citations
    28. CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17 The Journal of Experimental Medicine · 2024 · 32 citations
    29. Skin Wound Healing Elsevier eBooks · 2016 · 5 citations
    30. Granulocyte colony stimulating factor promotes scarless tissue regeneration Cell Reports · 2024 · 4 citations