May 2018 in “Journal of Investigative Dermatology” Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.
May 2018 in “Journal of Investigative Dermatology” Mint water extract boosts protective enzymes in skin cells.
May 2018 in “Journal of Investigative Dermatology” Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.
May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin heals with scars because only one type of fibroblast is used, not a mix.
May 2018 in “Journal of Investigative Dermatology” The role of γδT-cells in causing alopecia areata remains unclear.
May 2018 in “Journal of Investigative Dermatology” Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
March 2017 in “Fundamental & Clinical Pharmacology” The model and estimator can predict drug exposure in kidney transplant patients well.
May 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” M2 macrophages help hair regrowth in wounds by making growth factors.
May 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
12 citations,
February 2018 in “Scientific Reports” Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.
January 2024 in “International Journal of Molecular Sciences” Blocking the protein CXCL12 with a specific antibody can increase hair growth in common hair loss conditions.
April 2023 in “Chinese Medical Journal” 695 citations,
October 2011 in “Cell stem cell” Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
263 citations,
February 2020 in “International journal of molecular sciences” ADSCs help in wound healing and skin regeneration but need more research for full understanding.
173 citations,
September 2015 in “Developmental cell” The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
142 citations,
March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
98 citations,
March 2019 in “Frontiers in immunology” Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
53 citations,
April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
45 citations,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
37 citations,
May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
28 citations,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
28 citations,
June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
26 citations,
July 2021 in “Frontiers in Cell and Developmental Biology” The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
25 citations,
December 2021 in “Stem Cell Research & Therapy” MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
21 citations,
August 2017 in “Journal of veterinary internal medicine” Combining amino acid and stem cell therapy may help manage hepatocutaneous syndrome in dogs.