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This review examines advancements in "smart" hydrogel dressings for complex wound healing, highlighting innovations in materials that provide multifunctionality, such as responsive drug delivery and regenerative capabilities. The study also addresses potential challenges in clinical application, like manufacturing and regulatory hurdles.

This study observed that transgenic mice with overexpression of HE4 developed keratitis and severe corneal opacity, suggesting that HE4 may significantly influence keratopathy and inflammatory responses in the eye.

This study found that LGR5 is uniquely expressed in human corneal endothelial cells and maintains endothelial cell phenotypes while inhibiting mesenchymal transformation through the Wnt pathway.

This review discusses recent advances in scarless wound healing, focusing on strategies to create pro-regenerative scaffolds for repairing damaged skin, and reports no new clinical results.

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

This study found that α-13′-carboxychromanol significantly accelerated wound healing and improved tissue quality in a mouse model, especially when delivered with bacterial nanocellulose under diabetic conditions.

In this study involving adult mice, the researchers identified that double-stranded RNA-mediated activation of toll-like receptor 3 stimulates wound-induced hair neogenesis, potentially reflecting mechanisms used in facial rejuvenation treatments.

In this study, researchers found that wound healing in mouse skin recruits diverse fibroblasts, including myeloid-derived cells, which contribute to regenerating adipocytes.

This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.

This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.

This study suggests that wounding skin in adult mice can trigger new hair follicle formation, indicating mammalian skin may have greater regenerative capacity than previously thought.

This review explores the role of nanotechnology in wound healing, highlighting its potential through antimicrobial properties, selective inflammatory action, angiogenesis promotion, and its use in drug and gene delivery.

This review discusses the developmental regulation of wound healing mechanisms in mammals, focusing on the role of the Wnt and TGF‐β signaling pathways, and reports no new clinical findings.

This study found that tannic acid accelerated wound healing in rats by modulating inflammatory cytokines, increasing growth factors, and activating the Erk 1/2 pathway.

This study found that the acceleration of endothelial to mesenchymal transition due to loss of Notch signaling led to delayed wound healing and increased scarring in skin wounds.

This study found that allogeneic platelet gel significantly improved healing in non-healing chronic lower leg ulcers compared to hydrogel treatment.

This study found that ethanolic leaves extract of Hibiscus rosa-sinensis L. exhibited strong antioxidant activity and enhanced wound healing properties in mice, showing reasonable safety in toxicological evaluations without severe alterations.

This study found that adipose-derived mesenchymal stem cells from type 2 diabetes mice were slightly less effective, yet had comparable therapeutic effects on wound healing compared to non-diabetic controls.

This study found that gelatin microspheres loaded with platelet-rich plasma enhanced wound healing in rats by improving inflammatory and angiogenic responses compared to untreated wounds or PRP alone.

In this study, oil body-bound oleosin-rhFGF-10 was more efficiently absorbed through the skin and enhanced wound healing and hair growth in mice, compared to prokaryotically-expressed rhFGF-10.

This study suggests that using growth factors and ADSC-conditioned medium can enhance keratinocyte viability and migration in epidermal transplantation, potentially improving chronic wound healing rates with a patient-dependent effect.

This review discusses the similarities between wound healing and embryonic development, focusing on signaling pathways and their potential for developing new wound healing strategies, and reports no new clinical results.

This study reports that among rats with penile fractures, those treated with primary repair plus homologous platelet-rich plasma showed the best healing compared to other treatment methods.

In this animal study, the researchers found that DPP4 plays a crucial role in scar formation and wound-induced hair follicle neogenesis in mice, impacting regenerative repair.

This review revisits the mechanisms of wound induced hair follicle neogenesis in mice and concludes that the process involves canonical WNT signaling activated by Fgf9 from γδ T cells, but more research is needed to fully understand its cellular bases.

This study found that in vivo confocal scanning laser microscopy accurately quantifies neogenic hair follicles in mice, producing results similar to histology while avoiding fixation artifacts.

This study found that a newly developed mouse ear punch model effectively demonstrated that radiation significantly delays wound healing and may be used to study combined radiation and wound injury mechanisms.

In this study, wounds treated with a combination of 0.02% Decamethoxine and Blastomunil showed enhanced healing and epithelization by the 14th day, leveraging the immunomodulatory and antimicrobial properties of the agents.

This study found that Schistosoma mansoni cercariae stimulate epidermal keratinocytes in mice, initiating pro-inflammatory responses and barrier repair mechanisms akin to those in wound healing.

This review summarizes the role of G-protein-coupled receptors in wound healing and reports no new clinical results, highlighting their importance in signaling pathways and recent discoveries in their functions.