Regeneration of Chronic Wounds with Allogeneic Platelet Gel Versus Hydrogel Treatment: A Prospective Study

    January 2018 in “ Acta Clinica Croatica ”
    Danijela Semenič
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    Studysummary This study found that allogeneic platelet gel significantly improved healing in non-healing chronic lower leg ulcers compared to hydrogel treatment. Our plain-language summary of this paper — not a Tressless recommendation.
    The study evaluated the efficacy and safety of allogeneic platelet gel versus hydrogel in treating chronic lower leg ulcers in 60 patients. The randomized, double-blind, placebo-controlled trial showed that platelet gel significantly improved wound healing compared to hydrogel. After 6 months, the experimental group treated with platelet gel saw a reduction in mean wound area to 35.01% of the initial size, while the control group treated with hydrogel only reduced to 89.95%. Additionally, wound circumference decreased more in the platelet gel group (54.62%) compared to the hydrogel group (91.28%). The study concluded that allogeneic platelet gel was an effective treatment for non-healing chronic wounds.
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