Regeneration of Chronic Wounds with Allogeneic Platelet Gel Versus Hydrogel Treatment: A Prospective Study

The study evaluated the efficacy and safety of allogeneic platelet gel versus hydrogel in treating chronic lower leg ulcers in 60 patients. The randomized, double-blind, placebo-controlled trial showed that platelet gel significantly improved wound healing compared to hydrogel. After 6 months, the experimental group treated with platelet gel saw a reduction in mean wound area to 35.01% of the initial size, while the control group treated with hydrogel only reduced to 89.95%. Additionally, wound circumference decreased more in the platelet gel group (54.62%) compared to the hydrogel group (91.28%). The study concluded that allogeneic platelet gel was an effective treatment for non-healing chronic wounds.