The Effect of Platelet-Rich Plasma on Wound Healing in the Repair of Experimental Penile Fractures

    July 2021 in “ Indian Journal of Animal Research ”
    Ebuzer Düz, Burhan Beğer, Kamil Sağlam, Ebuzer Düz, Serkan Yıldırım
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    Studysummary This study reports that among rats with penile fractures, those treated with primary repair plus homologous platelet-rich plasma showed the best healing compared to other treatment methods. Our plain-language summary of this paper — not a Tressless recommendation.
    The study investigated the effect of platelet-rich plasma (PRP) on wound healing in rats with experimental penile fractures. Thirty-five rats were divided into five groups, including conservative treatment, bandage application, primary repair, primary repair with PRP, and a non-operative control group. The results showed that the primary repair combined with PRP led to the best healing outcomes, with improved clinical and histopathological findings compared to other groups. In contrast, conservative treatments resulted in persistent fracture formats and complications such as infection, edema, excessive fibrosis, and hyperemia.
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