Effects of Platelet-Rich Fibrin on Repair and Healing Chronic Refractory Wounds in Rats by Regulating Wnt/β-Catenin Signaling Pathway
January 2025
in “
Advances in Dermatology and Allergology
”
TLDR Platelet-rich fibrin helps heal stubborn wounds in rats by reducing inflammation and boosting tissue repair.
Platelet-rich fibrin (PRF) has been shown to enhance the repair and healing of chronic refractory wounds in rats. This is achieved by reducing inflammation on the ulcer surface and promoting collagen fiber deposition and angiogenesis. The underlying mechanism is likely related to the activation of the Wnt/β-catenin signaling pathway.
