Effect of Platelet Rich Fibrin on Wound Healing Time After Revascularization

    January 2025 in “ Acta Clinica Croatica
    Ana Adžić-Kapitanović
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    Studysummary This pilot study found that using platelet rich fibrin in combination with dressings after revascularization surgery in patients with critical limb ischemia accelerated wound healing compared to dressings alone. Our plain-language summary of this paper — not a Tressless recommendation.
    This pilot study investigated the effect of platelet rich fibrin (PRF) on wound healing time after revascularization in patients with peripheral arterial disease. Patients treated with PRF in combination with dressings experienced a significantly faster average wound healing time of 5 weeks compared to 8.5 weeks for those treated with dressings alone. Additionally, some patients in the dressing-only group required extended amputation. The study concludes that PRF can be safely used to enhance wound healing in vascular pathology.
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