Overexpression of HE4/WFDC2 Gene in Mice Leads to Keratitis and Corneal Opacity

    January 2025 in “ Open Life Sciences
    Lingjin Tuo, T Y Zhang, X. Xu, Jian Lin, Fengchao Wang, Hao Xu, Shi-Wen Jiang
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    Studysummary This study observed that transgenic mice with overexpression of HE4 developed keratitis and severe corneal opacity, suggesting that HE4 may significantly influence keratopathy and inflammatory responses in the eye.
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