Characterization of Four New Genes in the Ovine KAP19 Family

    July 2025 in “ International Journal of Molecular Sciences ”
    Lingrong Bai, Huitong Zhou, Jianning He … Jon G. H. Hickford
    Studysummary This genetic study identified four new keratin-associated protein genes in sheep, revealing significant sequence variation and suggesting complex evolutionary dynamics, with unique variants in some sheep breeds linking them to Romanov sheep ancestry.
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    Research cited in this study 12

    1. Genetics of Wool and Cashmere Fibre: Progress, Challenges, and Future Research Animals · 2024
    2. Characterization of Three Ovine KRTAP13 Family Genes and Their Association with Wool Traits in Chinese Tan Sheep Animals · 2024
    3. Characterisation of Ovine KRTAP19-3 and Its Impact on Wool Traits in Chinese Tan Sheep Animals · 2024
    4. Exploring Variation in Ovine KRTAP19-5 and Its Effect on Fine Wool Fiber Curvature in Chinese Tan Sheep Animals · 2024
    5. The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes International journal of molecular sciences · 2021
    6. Identification of Ovine KRTAP28-1 and Its Association with Wool Fiber Diameter Animals · 2019
    7. Molecular Characterization of Caprine KRTAP13-3 in Liaoning Cashmere Goat in China Journal of Applied Animal Research · 2013
    8. Annotation of Sheep Keratin Intermediate Filament Genes and Their Patterns of Expression Experimental Dermatology · 2011
    9. Biology of the Wool Follicle: An Excursion into a Unique Tissue Interaction System Waiting to Be Rediscovered Experimental Dermatology · 2006
    10. Human KAP Genes: Only Half of It? Extensive Size Polymorphisms in Hair Keratin-Associated Protein Genes ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    11. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1 Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    12. The Role of Keratin Proteins and Their Genes in the Growth, Structure, and Properties of Hair Birkhäuser Basel eBooks · 1997