Characterization of Three Ovine KRTAP13 Family Genes and Their Association with Wool Traits in Chinese Tan Sheep

October 2024 in “ Animals ”

Lingrong Bai, Huitong Zhou, Jianning He, Jinzhong Tao, Jon G. H. Hickford

Studysummary This study identified three genes in the ovine KAP13 family on chromosome 1 and found that a specific allele of KRTAP13-2 is associated with improved wool fibre diameter uniformity in Chinese Tan sheep, suggesting its potential use as a marker for enhancing wool traits.

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research Exploring Variation in Ovine KRTAP19-5 and Its Effect on Fine Wool Fiber Curvature in Chinese Tan Sheep

4 citations , July 2024 in “Animals”

In this study on Chinese Tan sheep, researchers discovered a variant of the KRTAP19-5 gene associated with decreased curvature of fine wool fibres, highlighting potential genetic markers for improving wool quality.

research Ovine KRTAP36-2: A New Keratin-Associated Protein Gene Related to Variation in Wool Yield

November 2023 in “Genes”

This study identified a new gene in sheep, KRTAP36-2, discovering variants associated with wool yield. Variations in this gene were linked to the efficiency of fleece conversion from greasy to clean, which may enhance wool production.

research The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes

10 citations , November 2021 in “International journal of molecular sciences”

This review discusses the role of keratin-associated proteins in the growth and characteristics of wool and hair fibres from sheep and goats, and highlights areas for future research, but it presents no new findings.

research Variation In The Ovine Keratin-Associated Protein 15-1 Gene Affects Wool Yield

18 citations , September 2018 in “The Journal of Agricultural Science”

In this study, the presence of certain KAP15-1 gene variants in sheep was associated with differences in wool yield and fiber characteristics.

research Identification of the Keratin-Associated Protein 13-3 (KAP13-3) Gene in Sheep

26 citations , January 2011 in “Open Journal of Genetics”

In this study, researchers identified five unique sequences of the ovine KAP13-3 gene, with potential implications for wool traits due to observed amino acid changes.

research Characterization and Expression Analysis of the Hair Keratin Associated Protein KAP26.1

50 citations , July 2008 in “British Journal of Dermatology”

research Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino Acid Composition and Repeat Structure

51 citations , January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study identified a novel keratin-associated protein, KAP24.1, which is specifically expressed in the human scalp and located in the hair cuticle.

research Human KAP Genes: Only Half of It? Extensive Size Polymorphisms in Hair Keratin-Associated Protein Genes

53 citations , June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

This article reviews extensive genetic polymorphisms in the keratin-associated proteins of human hair, indicating complexity but reporting no new clinical results and calls for further research on their potential impact on hair structure.

research Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1

100 citations , December 2002 in “Journal of biological chemistry/The Journal of biological chemistry”

This study identified a domain on human chromosome 21q22.1 containing various high glycine-tyrosine and high sulfur keratin-associated protein genes, revealing their diverse expression in hair-forming cells.

Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

98 citations , June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

This study identified a cluster of genes on chromosome 17 related to hair keratin-associated proteins, including 37 genes forming seven multigene families, localized in the hair shaft's upper cortex.

research Isolation and Characterization of a Putative Keratin-Associated Protein Gene Expressed in Embryonic Skin of Mice

22 citations , July 1998 in “Journal of Investigative Dermatology”

This study identified and characterized a gene called 4C32, which is expressed in the periderm of embryonic mouse skin and has a structure similar to keratin-associated proteins.

research The Role of Keratin Proteins and Their Genes in the Growth, Structure, and Properties of Hair

228 citations , January 1997 in “Birkhäuser Basel eBooks”

This article integrates existing literature on hair follicle structure and formation at the cellular and molecular level, reporting no new findings.

research The Keratin Proteins and Genes of Wool and Hair

15 citations , January 1996 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)”

This review discusses the structural knowledge of wool keratin proteins and genes, reports no new findings, and highlights promising directions such as keratin gene regulation.