January 2024 in “GeroScience” This review explores how radiation-induced hair graying can be used as a model to study the mechanisms behind hair graying, focusing on cellular senescence and potential therapeutic targets to address age-related changes. Results are not provided.
This study found that in a rat model of alopecia, combining low-level laser therapy with Neoptide treatment resulted in better hair regrowth compared to either treatment used alone.
January 1977 in “Case Reports in Medicine” This article discusses ovarian steroid cell tumors, which can produce testosterone and manifest symptoms like hirsutism, emphasizing surgery as the primary treatment, but reports no new clinical findings.
39 citations
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April 2015 in “Regeneration” This review discusses the regenerative processes of lizard tails, particularly focusing on the diversity in blastema development across different species, and reports no new findings.
31 citations
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November 2014 in “Investigative Ophthalmology & Visual Science” This study reported that in rat retinas under high pressure, allopregnanolone synthesis increased and helped reduce pressure-induced damage through GABAA receptors, suggesting potential therapeutic use in glaucoma.
11 citations
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August 1997 in “Expert Opinion on Therapeutic Patents” This review discusses nearly 70 patent applications for the treatment of androgenetic alopecia and other hair conditions, highlighting the mechanisms of action explored but reports no clinical results.
1 citations
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September 2025 in “Cureus” In this study, the ChatGPT-5 model accurately answered 76.47% of questions on the Polish endocrinology specialty exam, surpassing the 60% passing threshold, yet its role in clinical decision-making remains uncertain, highlighting the need for further research.
130 citations
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February 2018 in “Journal of Investigative Dermatology” This study found that tofacitinib led to ≥50% hair regrowth in eight out of twelve patients with moderate to severe alopecia areata, suggesting a potential benefit for using JAK inhibitors in treating this condition.
37 citations
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January 2016 in “Drug design, development and therapy” This review discusses the use of tofacitinib as a treatment for plaque psoriasis, highlighting its efficacy and safety in clinical trials, but notes unresolved questions regarding long-term safety.
34 citations
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December 2015 in “Neuroscience & Biobehavioral Reviews” In this study, several compounds, including estrogen and Dutasteride, showed neuroprotective effects on dopaminergic neurons in an MPTP mouse model of Parkinson's disease.
13 citations
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September 2019 in “Scientific Reports” In this study, high levels of the protein Flii in mice were associated with worsened symptoms and inflammation in ulcerative colitis, suggesting Flii may inhibit mucosal healing.
12 citations
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November 2003 in “Journal of the American Academy of Dermatology” This study found hair regrowth in the majority of AA-affected mice and rats treated with diphencyprone, suggesting its potential utility for understanding human alopecia areata and the drug's therapeutic action.
3 citations
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January 2022 in “PLoS ONE” In this study using a rat full-thickness burn model, the amnion bilayer dressing showed better healing and skin recovery than the standard protocol, including quicker complete healing and restored skin appendages.
3 citations
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January 2016 in “Annals of Dermatology” This study suggests that 2% minoxidil and Kerium may promote hair regrowth in rats, while Aminexil showed the least effect among tested treatments; human-use products varied in efficacy in this animal model.
1 citations
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June 2023 in “Radiation oncology journal” This study suggests that low-dose radiotherapy may lead to temporary neurological improvements in some Alzheimer's patients, with 20% showing cognitive improvement at 6 months; it was well-tolerated, though larger trials are needed for confirmation.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” This study found that mesotherapy with placenta polypeptide injection significantly reduced skin inflammation and improved aesthetic outcomes in adults with moderate-to-severe sensitive skin, without increasing adverse events compared to controls.
December 2025 in “Drug Discovery and Molecular Docking (DDMD)” This review highlights how single-cell transcriptomics has advanced understanding of tissue regeneration by revealing cellular diversity and key molecular interactions in animal models, despite methodological challenges, suggesting future applications in developing targeted regenerative therapies.
December 2025 in “Scientific Reports” In this study, researchers observed that DHEA-induced PCOS rats experienced significant changes in gut microbiota and metabolic profiles, particularly affecting steroid and lipid metabolism, suggesting the gut-ovary axis may play a role in the pathogenesis of PCOS.
January 2025 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” This review highlights morphological factors contributing to age-related alopecia and suggests further research to understand and potentially mitigate cellular aging processes affecting hair quality.
January 2025 in “Bright Sky Publications eBooks” This abstract does not report specific research findings but describes a book titled "Medical Physics and Laser Technology: Advancements and Applications in Modern Healthcare," authored by Zahraa Zuhair Ghafel Saeid and colleagues, which is available for purchase.
November 2023 in “Frontiers in veterinary science” In this study, researchers used yaks as a natural model to investigate hair growth mechanisms, overcoming previous limitations by establishing in vitro models of hair follicle-associated cells and optimizing methods for cell culture and differentiation.
This study investigates whether adding 30% supramolecular salicylic acid to conventional treatment for mild to moderate acne vulgaris is safe and effective, though specific results are not reported in the abstract.
December 2025 in “Nature Communications” This study demonstrated that skin organoids derived from human stem cells can model cutaneous tuberculosis, revealing that fibrosis development in Mycobacterium tuberculosis-infected organoids is linked to the PI3K-AKT and AP1 pathways in fibroblasts, and suggesting the potential for antifibrotic treatment evaluation.
23 citations
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July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.
16 citations
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September 2016 in “Neuropharmacology” This study suggests that in an ex vivo rat glaucoma model, TSPO activation is involved in Allopregnanolone synthesis and may help prevent retinal damage, with TSPO agonists as potential therapeutic agents.
13 citations
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January 2022 in “Stem cell reviews and reports” This study found that using cultured mesenchymal stem cells from mouse whisker hair follicle outer root sheath in wound healing reduced inflammation, accelerated closure, and resulted in less hypertrophic scarring in mice.
4 citations
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February 2020 in “Cell & tissue research/Cell and tissue research” This study suggests that adult hair follicle stem cells can survive and potentially differentiate into neuronal cells after being transplanted in a mouse model of traumatic brain injury, indicating promise for TBI therapy.
2 citations
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March 2025 in “International Journal of Advanced Science and Engineering” This review highlights that nanoemulsions, especially those with droplet sizes under 200 nm, show promise in pharmaceuticals and cosmetics by improving drug stability, bioavailability, and reducing side effects, with potential applications in CNS diseases, cancer treatments, and skincare products.
1 citations
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January 2024 in “IEEE access” This study found that their proposed method for facial image restoration using Denoising Diffusion Probabilistic Models produced higher-quality results compared to traditional methods, particularly improving face recognition accuracy with different types of masks.
June 2026 in “Research Square” This study evaluated an herbal emulgel formulation containing extracts from Wedelia chinensis and Cassytha filiformis for hair growth promotion in rats, finding that the combined formulation significantly increased hair growth compared to both individual extracts and the control group.