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The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.

Activin A speeds up ear hair cell differentiation, while Follistatin slows it down.

Pygo2 is important for early growth and progression of intestinal tumors, and could be a target for treating cancers with certain mutations.

Two growth factors, PDGF and FGF2, can potentially be used together to grow enough cells for a hair loss treatment, but their exact function on human cells needs further confirmation.

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Hair follicles help attract immune cells to the skin during stress.

Mitochondrial reactive oxygen species are essential for skin and hair development.

Vitamin D is important for bones, hair, blood pressure, and breast development.

YAP and TAZ are crucial for skin cell growth and repair.

Notch signalling helps skin cells differentiate and prevents tumors.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Targeting and modifying the stem cell niche can improve regenerative therapies.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Hair growth and development are controlled by specific signaling pathways.

Wounded skin cells can revert to stem cells and help heal.

Cannabinoids may help treat various skin conditions.

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.