24 citations
,
March 2020 in “Cells” This review provides an overview of natural product-derived small molecule modulators of the Wnt signaling pathway, exploring their potential as therapeutic agents for tissue regeneration and cancer treatment.
21 citations
,
February 2023 in “Pharmaceuticals” This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.
18 citations
,
November 2021 in “Anais Brasileiros de Dermatologia” This review examines the skin manifestations associated with COVID-19 but reports no new clinical findings, emphasizing the need for differential diagnoses to correlate skin symptoms with the virus.
18 citations
,
April 2016 in “The journal of immunology/The Journal of immunology” This study found that mesenchymal cells from different organs exhibit substantial heterogeneity, with thymic mesenchymal cells particularly adapted for interacting with epithelial and hematolymphoid cells in high-apoptosis environments.
16 citations
,
April 2016 in “Medicine” This study described a case where lupus erythematosus panniculitis preceded the diagnosis of systemic lupus erythematosus, highlighting the need for regular follow-ups in LEP patients for potential SLE development.
16 citations
,
April 2025 in “Foods” This study highlights the diverse applications of *Perilla frutescens* in traditional medicine, cuisine, and industrial settings, noting its significant antioxidant and antimicrobial properties in experimental models, as well as research efforts to enhance its bioactive content and ensure safety and standardization.
15 citations
,
January 2022 in “Immune Network/Immune network” This review summarizes the pathophysiology and immune mechanisms of inflammatory skin diseases like psoriasis and atopic dermatitis, highlighting the therapeutic potential of targeted immunotherapies, but reports no new clinical results.
15 citations
,
October 2021 in “Frontiers in Pharmacology” This commentary discusses the potential of natural volatiles in medical aromatherapy, highlighting their ability to synergize with other drugs and modulate biological processes, but reports no new results.
14 citations
,
January 2014 in “Anais Brasileiros de Dermatologia” This study found that low BMI may increase the risk of developing chilblains in individuals exposed to cold weather, with many patients experiencing recurrent lesions each winter.
13 citations
,
September 2022 in “Biomolecules” This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.
12 citations
,
June 2020 in “Lupus” This study found that treating a murine model of systemic lupus erythematosus with early and optimally dosed mesenchymal stem cells effectively suppressed disease severity.
12 citations
,
December 2023 in “Antioxidants” In this study, researchers found that blackberry leaves exhibited higher liposoluble antioxidant levels and inhibited lipid peroxidation more effectively than raspberry leaves, while raspberry leaves showed greater water-soluble antioxidant content and hydroxyl radical inhibition in vitro.
9 citations
,
December 2021 in “Androgens” This review explores how androgen administration might help alleviate inflammation and mitochondrial impairment in traumatic brain injury but reports no new experimental findings, calling attention to the need for further investigation.
9 citations
,
January 2023 in “Langmuir” This study presents a method for directly measuring the solubility of solid chemicals in the skin's stratum corneum under various humidity conditions, emphasizing its importance for dermal drug delivery and chemical safety assessments.
9 citations
,
December 2021 in “Molecules” This study found that certain metabolites from the plants Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana may support hair follicle growth by promoting dermal papilla cell proliferation, supporting their traditional use in hair care.
8 citations
,
July 2021 in “F1000Research” This review discusses the potential of plant-derived phytochemicals as alternatives to 5-alpha-Reductase inhibitors in treating prostate cancer, highlighting possible benefits like reduced side effects, but it reports no new findings.
7 citations
,
October 2008 in “Arthritis Care & Research” This case report describes a 32-year-old woman with a history of undifferentiated connective tissue disease who presented with cardiogenic shock, and endomyocardial biopsy revealed giant cell myocarditis, possibly indicating an association with her autoimmune condition.
6 citations
,
July 2024 in “Heliyon” This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.
6 citations
,
February 2021 in “Frontiers in Neurology” This study found that cyclosporine-A might significantly increase the risk of cerebral venous and arterial thrombosis in patients with aplastic anemia.
6 citations
,
April 2010 in “Arthritis Care & Research” This case report describes a 39-year-old Thai woman with systemic lupus erythematosus whose symptoms, initially resembling an autoimmune myositis, were determined to be caused by tuberculous myositis, with improvement noted upon antituberculous treatment.
6 citations
,
September 2021 in “Autophagy” In this study on mouse preputial glands, suppressing ATG7-dependent autophagy delayed age-related changes, affected lipid metabolism, and reduced pheromone production, highlighting autophagy's roles in glandular homeostasis and cell breakdown.
5 citations
,
May 2022 in “International Journal of Surgery Case Reports” This case study reported the successful management of cardiac tamponade in a pregnant woman with systemic lupus erythematosus using pericardiocentesis and immunosuppressant therapy, although the patient declined cyclophosphamide treatment.
5 citations
,
August 2019 in “International Journal of Women's Dermatology” This article discusses various types of alopecia more common in African-American individuals and reports no clinical results; it highlights the importance of recognizing and differentiating these subtypes for diagnosis and treatment.
4 citations
,
April 2025 in “Frontiers in Immunology” This article discusses the potential of extracellular vesicles for developing precise psychiatric therapies and the need for interdisciplinary collaboration, but reports no new clinical results.
4 citations
,
October 2025 in “Molecules” This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.
4 citations
,
January 2014 in “Stem Cell Discovery” This review discusses the various types of stem cells, including their potential applications in therapy, and reports the challenges associated with safe stem cell treatment, with no new clinical results presented.
3 citations
,
February 2021 in “Pediatric rheumatology online journal” This case study described a 16-year-old girl with systemic lupus erythematosus and trisomy X, suggesting that these patients might be at higher risk for avascular necrosis and osteoporosis.
3 citations
,
January 2021 in “Postepy Dermatologii I Alergologii” Yes, smoking damages your skin.
3 citations
,
February 2023 in “Journal of Experimental Pharmacology” This study found that LHE may prevent and reverse testosterone-induced prostatic hyperplasia, supporting the traditional use of Kigelia africana for some reproductive system disorders.
2 citations
,
October 2022 in “Rheumato” This case report from Tishreen Hospital highlights that although rare, cardiac tamponade and acute surgical abdomen due to acute peritonitis and ascites can occur concurrently as initial presentations of systemic lupus erythematosus.