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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Minoxidil effectively lowers blood pressure with few side effects.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Minoxidil can harm dog's heart.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Some plants with flavonoids may help treat hair loss and promote hair growth.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Finasteride effectively prevents biofilm formation and treats preformed biofilms, but requires high doses.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.