TLDR Finasteride effectively prevents biofilm formation and treats preformed biofilms, but requires high doses.
The study investigated the effectiveness of finasteride against Candida albicans urinary biofilm formation and filamentation. The results showed that finasteride alone was highly effective in preventing biofilm formation and treating preformed biofilms. Finasteride also exhibited synergistic activity in combination with fluconazole. However, high doses of finasteride were required, limiting its clinical utility. The study suggests that targeting virulence factors, such as biofilm formation and filamentation, may be a potential strategy for treating C. albicans infections.
14 citations,
January 2011 in “Urologia Internationalis” Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.
108 citations,
February 2008 in “The Journal of urology/The journal of urology” Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
93 citations,
January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
70 citations,
June 1993 in “Biochemistry” Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
11 citations,
February 2004 in “Clinical and Experimental Ophthalmology” Taking Propecia might lead to the development of cataracts.
June 2024 in “Georgetown medical review” Finasteride treats hair loss but may cause low libido, erectile issues, and depression.
June 2017 in “Reactions Weekly” Finasteride (Propecia) may cause depression and suicidal thoughts; stop use and inform a healthcare professional if symptoms develop.
3 citations,
June 2004 in “Annales De Dermatologie Et De Venereologie” Four new cases of gynecomastia (male breast enlargement) linked to finasteride (Propecia) have been found.
Finasteride is popular for treating male hair loss but may increase the risk of serious prostate cancer and has other potential side effects.
2 citations,
January 2003 in “Journal of Clinical Dermatology”
