Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model

    January 2011 in “ Urologia Internationalis ”
    Choong Hwan Lee, U-Syn Ha, Seung Hyuk Yim, Hyun Lee, Dong Hwan Sohn, Chang Soo Han, Yong-Hyun Cho
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    TLDR Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.
    This study investigated whether finasteride has a preventive effect on chronic bacterial prostatitis (CBP) using an animal model. Results showed that finasteride significantly reduced bacterial infection and decreased inflammatory cell infiltration in prostatic tissue compared with the control group. The group given both finasteride and antibiotic showed a greater inhibition of bacterial infection in the tissue than those given either finasteride or antibiotic alone. The study suggests the possibility that finasteride has a preventive effect on the development of CBP, although further research is needed.
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