Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model

January 2011 in “ Urologia Internationalis ”

Choong Hwan Lee, U-Syn Ha, Seung Hyuk Yim, Hyun Lee, Dong Hwan Sohn, Chang Soo Han, Yong-Hyun Cho

finasteride chronic bacterial prostatitis prostatic tissue inflammatory cell infiltration Propecia

TLDR Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.

This study investigated whether finasteride has a preventive effect on chronic bacterial prostatitis (CBP) using an animal model. Results showed that finasteride significantly reduced bacterial infection and decreased inflammatory cell infiltration in prostatic tissue compared with the control group. The group given both finasteride and antibiotic showed a greater inhibition of bacterial infection in the tissue than those given either finasteride or antibiotic alone. The study suggests the possibility that finasteride has a preventive effect on the development of CBP, although further research is needed.

View this study on karger.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Creatine made all my high DHT symptoms return

in Research/Science 78 upvotes 1 month ago

Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 57 upvotes 1 month ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community Derm says my hair loss (diffuse) is from seborrheic dermatitis. Anyone else have experience with this? I was already prepared to jump on fin min

in Research/Science 25 upvotes 3 weeks ago

Seborrheic dermatitis can cause hair loss, and treatments like ketoconazole shampoo, topical steroids, and oral antifungals may help. Some consider using finasteride and minoxidil for hair loss despite dermatitis.

community Why balding gets worse in every generation?

in Chat 81 upvotes 6 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community How uninformed the general public is about hair loss

in Chat 318 upvotes 10 months ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

Similar Research

5 / 1000+ results

research Diseases Of The Canine Prostate Gland

1 citations, August 2022 in “Veterinary medicine and science”

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

research Anti-Inflammatory and Anti-Hyperplastic Effect of Bazhengsan in a Male Rat Model of Chronic Nonbacterial Prostatitis

7 citations, February 2019 in “Journal of pharmacological sciences”

Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.

Dual Deficiency of Melatonin and Dihydrotestosterone Promotes Stromal Cell Damage and Mediates Prostatitis via the cGAS-STING Pathway in Sleep-Deprived Mice

research Dual Deficiency of Melatonin and Dihydrotestosterone Promotes Stromal Cell Damage and Mediates Prostatitis via the cGAS-STING Pathway in Sleep-Deprived Mice

March 2024 in “Cell communication and signaling”

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

research Impact of Cernitin on Induced Chronic Prostatitis in Animal Model for Understanding Management of Lower Urinary Tract Symptoms

1 citations, March 2021 in “Phytomedicine plus”

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

research Saw Palmetto and Finasteride in the Treatment of Category-III Prostatitis/Chronic Pelvic Pain Syndrome

5 citations, March 2005 in “Current Urology Reports”

Saw palmetto helps with nighttime urination and urine flow, similar to finasteride.