665 citations,
April 2016 in “Nature communications” Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
546 citations,
February 2008 in “PLANT PHYSIOLOGY” OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.
231 citations,
October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
218 citations,
September 2012 in “Gastroenterology” Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
214 citations,
September 2015 in “Stem Cells Translational Medicine” Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
188 citations,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
135 citations,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
124 citations,
July 2017 in “eLife” Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
109 citations,
February 2018 in “CB/Current biology” ERULUS controls root hair growth by regulating cell wall composition and pectin activity.
96 citations,
December 2018 in “Immunity” Targeting TGFβ can improve skin immunity in older people.
85 citations,
January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
79 citations,
December 2017 in “Cosmetics” Effective sunscreen formulations can reduce skin absorption and enhance protection.
74 citations,
January 2015 in “Asian Journal of Transfusion Science” Platelet-rich plasma (PRP) injections can effectively increase hair density and thickness in people with androgenic alopecia, without major side effects.
70 citations,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
68 citations,
August 2014 in “PeerJ” Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.
65 citations,
September 2014 in “Orphanet Journal of Rare Diseases” Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.
62 citations,
December 2007 in “Journal of biological chemistry/The Journal of biological chemistry” A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.
57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
45 citations,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
37 citations,
June 2019 in “Stem cells” Special particles from skin cells can promote hair growth by activating a specific growth signal.
31 citations,
April 2019 in “Journal of Cutaneous Pathology” Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.
29 citations,
April 2019 in “Acta neuropathologica communications” Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
29 citations,
September 2017 in “Genes” Selecting specific KRTAP26-1 gene variants can improve wool quality in sheep.
26 citations,
December 2019 in “Indian Journal of Dermatology, Venereology and Leprology” PRP combined with minoxidil is the most effective and safe treatment for male pattern baldness.
26 citations,
June 2016 in “Frontiers in Plant Science” Autofluorescence can sort plant cells without labeling.
19 citations,
May 2021 in “Clinical, Cosmetic and Investigational Dermatology” Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.
15 citations,
October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
15 citations,
July 2021 in “Bosnian Journal of Basic Medical Sciences” Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
14 citations,
April 2021 in “Heliyon” Pomegranate leaf extract may help with hair growth, dandruff, and lice.
14 citations,
November 2019 in “Materials” Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.