research Degeneration in Dermatopathology
The document concludes that understanding tissue degeneration is crucial for diagnosing skin lesions.
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690-720 / 1000+ results research Scoring Systems for Pemphigus
The Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score are the best tools for assessing pemphigus severity.
research Author Response: Lhx2 as a Progenitor-Intrinsic Modulator of Sonic Hedgehog Signaling During Early Retinal Neurogenesis
Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.
research STAT3 Inhibits Cell Proliferation at Least in Part Via Directly Negatively Regulating FST Gene Expression
STAT3 reduces FST gene activity and cell growth, affecting hair development and wool quality.
research Loss of Repressor Activator Protein 1 Precipitates Cardiac Aging in Mice via p53/PPARα Signaling
Loss of Rap1 protein speeds up heart aging in mice.
research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
research Generalized Glucocorticoid Resistance
Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.
research DNA Methylation Mediates LncRNA2919 Regulation of Hair Follicle Regeneration
DNA methylation controls lncRNA2919, which negatively affects hair growth.
research Ar/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia
The Ar/miR-221/IGF-1 pathway is involved in male pattern baldness, with miR-221 potentially being a new target for treatment.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Plasticity of Epithelial Stem Cells in Tissue Regeneration
Epithelial stem cells can adapt and help in tissue repair and regeneration.
research Emerging Interactions Between Skin Stem Cells and Their Niches
Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
research Cell Death by Cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research The Complex Relationship Between TFEB Transcription Factor Phosphorylation and Subcellular Localization
Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
research C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research O-Glycosylated Cell Wall Proteins Are Essential in Root Hair Growth
Proteins with added sugars are crucial for plant root hair growth.
research Integrin Signaling Regulates YAP/TAZ to Control Skin Homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
research ERG Induces Androgen Receptor-Mediated Regulation of SOX9 in Prostate Cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium
Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
research An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin
The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Dlx3 Is a Crucial Regulator of Hair Follicle Differentiation and Cycling
Dlx3 is essential for hair growth and regeneration.
research Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Epidermal Stem Cells in Wound Healing and Their Clinical Applications
Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
research The Vitamin D Receptor Is a Wnt Effector That Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis
Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research Dermal Fibroblasts in Cutaneous Development and Healing
Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
research RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome
Mutations in the RBPJ gene cause Adams-Oliver Syndrome.