TLDR The Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score are the best tools for assessing pemphigus severity.
The document reviews various scoring systems for assessing the severity of pemphigus, an autoimmune skin disease. The Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score are identified as the most valid and reliable tools, though the FDA prefers simpler scores like Investigator’s Global Assessments, which need further validation. Additionally, the document discusses the role of sex hormones in hair diseases, highlighting the progress and future research directions in this field. It also presents a study on the effectiveness of platelet-rich plasma for treating alopecia areata in 17 patients, finding it to be a safe and effective treatment. Lastly, it explores the role of epigenetic dysregulation in primary cutaneous mucinous carcinoma, suggesting that epigenetic changes may contribute to its pathobiology.
3 citations,
April 2023 in “Dermatologica Sinica” PRP treatment may help with alopecia areata, especially in newer cases.
April 2023 in “Dermatologica Sinica” Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.
3 citations,
July 2021 in “Aesthetic Plastic Surgery” PHAT may improve hair growth better than PRP alone.
6 citations,
May 2021 in “Aesthetic Surgery Journal” Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
April 2023 in “Dermatologica Sinica” Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.
4 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
53 citations,
June 2017 in “Skin appendage disorders” PRP treatment helps hair growth in most cases, but more research needed.
