Scoring Systems for Pemphigus

The document reviews various scoring systems for assessing the severity of pemphigus, an autoimmune skin disease. The Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score are identified as the most valid and reliable tools, though the FDA prefers simpler scores like Investigator’s Global Assessments, which need further validation. Additionally, the document discusses the role of sex hormones in hair diseases, highlighting the progress and future research directions in this field. It also presents a study on the effectiveness of platelet-rich plasma for treating alopecia areata in 17 patients, finding it to be a safe and effective treatment. Lastly, it explores the role of epigenetic dysregulation in primary cutaneous mucinous carcinoma, suggesting that epigenetic changes may contribute to its pathobiology.