June 2026 in “Open Access Research Journal of Biology and Pharmacy” This study used molecular docking simulations to identify approved drugs, including Bedaquiline and Telmisartan, with potential to treat Onchocerca volvulus infections by inhibiting key protein targets, suggesting these drugs could be repurposed for onchocerciasis treatment with further validation.
May 2026 in “Scientific Reports” This study explored the potential of stigmasterol as a treatment for androgenetic alopecia through various simulation techniques, finding promising interactions with key genes involved in hair loss, but further experimental validation is needed before clinical application.
January 2026 in “GSC Biological and Pharmaceutical Sciences” This study used molecular docking simulations to identify Adapalene, Diosmin, and Azelastine as promising drugs for repurposing against onchocerciasis by targeting proteins in the parasite and its endosymbiont; further research is needed to confirm their efficacy.
January 2026 in “New Journal of Chemistry” This study synthesized calcium citrate nanoparticles to improve the solubility and reduce the irritation of minoxidil solutions for treating androgenetic alopecia.
This review highlights that microtrauma, involving small intentional skin injuries, shows promise in stimulating hair growth in non-scarring alopecias by enhancing immune responses and increasing growth factor release, with methods like microneedling and PRP demonstrating efficacy.
June 2025 in “International Journal of Molecular Sciences” In this study, researchers used spatial transcriptomics to identify increased expression of genes linked to extracellular matrix organization and epithelial–mesenchymal transition in the progenitor cell regions of hair follicles in androgenetic alopecia patients, suggesting a possible role in progenitor cell loss and fibrogenic microenvironment development.
June 2025 in “Archives of Dermatological Research”
April 2025 in “Journal of Investigative Dermatology” This study found that elevated luteinizing hormone levels were significantly associated with female pattern hair loss, and implicated LH/LHR signaling in the aging and damage of hair follicles.
February 2025 in “Archives of Dermatological Research” Polynucleotides effectively promote hair regrowth in androgenetic alopecia without serious side effects.
October 2024 in “Archives of Dermatological Research” This study found distinct proteomic differences between male and female androgenetic alopecia, highlighting sex-specific molecular pathways and potential biomarkers for pattern hair loss.
October 2024 in “Photodermatology Photoimmunology & Photomedicine” In this study, participants with androgenetic alopecia who used an LED helmet emitting red and green light experienced significant improvements in hair growth measures, with red light showing superior results in increasing hair diameter and reducing vellus hair density over 6 months.
September 2024 in “Archives of Dermatological Research” This study found that both red and green LED therapies combined with a microneedling patch significantly improved hair density and diameter in androgenetic alopecia patients over 24 weeks, with no serious side effects and similar efficacy between the two light wavelengths.
August 2024 in “International Journal of Molecular Sciences” The study investigated immune cell patterns around the hair follicle infundibulum in androgenetic alopecia, revealing significant differences in immune signatures between patients with AGA and control donors, specifically noting an enrichment of CD4 cells in the patient group.
December 2023 in “Siriraj Medical Journal” This study found that 5% azelaic acid solution and 2% minoxidil solution both significantly increased hair density and shaft diameter in women with FPHL, with no significant differences between them.
November 2023 in “Translational Medicine Communications” In this study, researchers found that Derinat, a TRPCs inhibitor, reduced oxidative stress and prolonged the anagen phase of hair growth in mice, supporting its potential as a therapy for androgenetic alopecia by improving clinical outcomes and enhancing quality of life for those affected.
This review discusses the genetic differences between male and female pattern hair loss and highlights the uncertainty surrounding genetic factors in female pattern hair loss, but reports no clinical results.
June 2023 in “Research Square (Research Square)” In this study, researchers used spatial transcriptome profiling to identify immune disturbances in the peri-infundibular region of androgenetic alopecia patients’ hair follicles, finding increased CD4+ T cells with a bias toward Th2 immune responses compared to controls.
April 2023 in “JMIR Research Protocols” In this study, researchers are constructing a comprehensive data set from 997 adult participants in Japan to develop a statistical model that explores the relationships among various health parameters, aiming to enable personalized and preventive health care interventions based on empirical data.
This study aims to use a comprehensive health data set to develop a statistical model that can improve personalized and preventive health care by understanding relationships between various health parameters in individuals.
May 2021 in “Research Square”
January 2018 in “Springer eBooks” This review discusses the factors affecting laser hair removal results and adverse events, emphasizing the need for more research to determine optimal treatment parameters; it reports no new clinical findings.
May 2023 in “Blood cancer discovery” This study found that Finasteride significantly reduced the proliferation of acute myeloid leukemia cell lines by inhibiting androgen receptor activity.
December 2022 in “The Aging Male” This study found that in male patients, a lower right-handed 2D:4D digit ratio combined with older age correlated with increased severity risk of androgenetic alopecia.
1 citations
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April 2025 in “Cureus” In this in vitro study, pretreatment with Dead Sea water and saline magnetized water reduced UVB-induced DNA damage and inflammation markers in human keratinocyte cells, primarily through autophagy activation, suggesting potential use in topical products to prevent skin damage from UV exposure.
March 2024 in “International Seven Journal of Health Research” In this study, the authors synthesized recent literature on childhood alopecia areata, highlighting its clinical manifestations and management strategies, which include individualized treatments and psychosocial support to mitigate emotional and social impacts on affected children.
February 1999 in “Analytical Sciences” A new antiandrogen compound was made and its detailed three-dimensional shape was described.
13 citations
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November 2017 in “Journal of Cellular and Molecular Medicine” This workshop reviewed various roles of endoplasmic reticulum chaperones, including calreticulin, in cellular signaling, disease states, and potential markers, but reports no new experimental findings.
December 2024 in “Globus: an international journal of medical science, engineering and technology.” This study found that 10% Citrus aurantium peel oil significantly promoted hair growth in ICR mice by reducing the time needed for hair growth initiation and completion, and by increasing hair length, follicle diameter, and count, showing potential as a hair growth agent.
April 2023 in “Journal of Investigative Dermatology” This study identified TGFβ-2 as a potential driver of progenitor cell loss in hair follicles from early androgenetic alopecia scalps, suggesting its role in the condition's molecular disturbances.