Spatial Transcriptome Reveals Disturbance of Peri-Infundibular Immune Infiltration in Androgenetic Alopecia

June 2023 in “ Research Square (Research Square) ”

Sasin Charoensuksira, Supasit Tantiwong, Juthapa Pongklaokam, Sirashat Hanvivattanakul, Piyaporn Surinlert, Aungkana Krajarng, Wilai Thanasarnaksorn, Suradej Hongeng, Saranyoo Ponnikorn

androgenetic alopecia peri-infundibular immune infiltration spatial transcriptome profiling CD4+ helper T cells T helper 2 response Th2 response Th1-cytotoxic response T cell subpopulations AGA PII Th2 cells Th1 cells

Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

Studysummary In this study, researchers used spatial transcriptome profiling to identify immune disturbances in the peri-infundibular region of androgenetic alopecia patients’ hair follicles, finding increased CD4+ T cells with a bias toward Th2 immune responses compared to controls.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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