Second-To-Fourth Digit Ratio and Age Predicting the Severity of Androgenetic Alopecia: A Cross-Sectional Study

December 2022 in “ The Aging Male ”

Wei-Chiao Chen, Wen-Li Hsu, Jeff Yi-Fu Chen, Nai-Hua Shih, Ching-Ying Wu

androgenetic alopecia 2D:4D ratio digit ratio age AGA

TLDR Lower 2D:4D ratio and older age increase the risk of severe hair loss in men.

This study investigated the relationship between the right-hand second-to-fourth digit ratio (2D:4D) and the severity of androgenetic alopecia (AGA) in male patients. The results showed that a lower 2D:4D ratio is associated with a higher risk and severity of AGA, which also increases with age. Specifically, patients aged 37.5 or older with a 2D:4D ratio below 0.947 were six times more likely to have moderate-to-severe AGA. The study suggests that combining 2D:4D ratio and age could serve as a non-invasive method to predict AGA severity.

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Second-To-Fourth Digit Ratio and Age Predicting the Severity of Androgenetic Alopecia: A Cross-Sectional Study

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research Second-To-Fourth Digit Ratio And Seborrheic Dermatitis In Males: A Cross-Sectional Study

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research Androgen Receptor Gene Polymorphisms and Risk for Androgenetic Alopecia: A Meta-Analysis

research Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla

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research Prevalence and Types of Androgenetic Alopecia in Shanghai, China: A Community-Based Study

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