In Silico Investigation of Possible Multi-Target Drugs Against Glutamate S-Transferase and Prolyl tRNA Synthetase in Onchocerca Volvulus

    June 2026 in “ Open Access Research Journal of Biology and Pharmacy ”
    Gabriel Chigozie Anizoba, Evangeline Chiazolam Nwaedozie, Ikemefuna Chijioke Uzochukwu, Igboeli Chukwuduziem Nnamdi
    Studysummary This study used molecular docking simulations to identify approved drugs, including Bedaquiline and Telmisartan, with potential to treat Onchocerca volvulus infections by inhibiting key protein targets, suggesting these drugs could be repurposed for onchocerciasis treatment with further validation.
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