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This review examines how mathematical modeling of the MAPK pathway, enhanced by single-cell proteomic data, improves understanding of regulatory mechanisms, predicts system behavior, and guides experimental research, emphasizing recent developments in modeling and inference.

This review discusses recent advances in using extracellular vesicles as a potential treatment for alopecia and highlights ongoing challenges in their clinical application and mass production; no new clinical results are reported.

This review summarizes recent advancements in using exosomes for promoting hair growth, finding that exosomes from various cells, like dermal papilla and mesenchymal stem cells, show promise as a potential new treatment route for alopecia.

In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.

This review discusses cell membrane-coated scaffolds in tissue engineering, emphasizing their potential to enhance therapeutic outcomes in regenerative medicine and reporting no new experimental results.

This review highlights recent research using single-cell RNA sequencing and machine learning in wound healing, revealing significant insights into fibroblast diversity, immune cell dynamics, and the spatial organization of cells, which may transform therapeutic strategies for chronic wounds, fibrosis, and tissue regeneration.

This review summarizes the roles of matricellular proteins in skin stem cell niches, highlighting their contribution to stem cell fate, self-renewal, and potential implications for wound healing and aging.

This review highlights recent advancements in microfluidics for 3D tissue model generation and discusses its applications in tissue engineering and high-throughput drug screening without reporting new experimental results.

This study concluded that terminal Schwann cells are essential for the maintenance and regeneration of mechanosensory lanceolate complexes at hair follicles in adult mice.

In this study, researchers found that connexin 43-negative cells in the basal layer of the epidermis could serve as markers for keratinocyte stem cells, aiding their identification and separation.

This review discusses the potential benefits of photobiomodulation for managing side effects of cancer therapy and provides specific guidelines for its use in supportive cancer care, without presenting new clinical results.

This review highlights the promising potential of using nanomedicine-based immunotherapy in tissue regeneration, detailing recent advances in nanocomposite biomaterials and the modulation of immune responses to create optimal environments for tissue repair.

This review discusses the role of the Wnt/β-catenin pathway in skin wound repair and explores how photobiomodulation may affect chronic wound healing, but it reports no new clinical results.

This perspective highlights how advancements in single-cell sequencing and digital pathology can help understand the complex mechanisms of immune responses, fibrosis, and tissue remodeling related to medical implants, aiming to address the challenges of implant-related tissue reactions reported in this study.

This review discusses current strategies and materials in tissue engineering for skin regeneration, emphasizing design approaches and suggesting directions for future research; it reports no new clinical findings.

This study summarizes the signaling molecules and extracellular components involved in epithelial–mesenchymal interactions, enhancing our understanding of hair follicle regeneration and skin wound healing, but reports no new experimental results.

This review explores the historical development of theories on physiological tissue regeneration, particularly focusing on peripheral nerve regeneration, and emphasizes the need for new experiments and perspectives without providing new empirical findings.

This review article analyzes the role of the WNT signaling pathway in skin development, wound healing, and mechanical stretching, emphasizing its importance in understanding and potentially advancing treatments for skin-related diseases.

In this review, the authors discuss how niche-specific immunometabolic regulation influences tissue repair across various organs by highlighting the complex, context-dependent interaction between immune metabolism and tissue-specific regenerative outcomes.

This review explores the potential roles of extracellular vesicles in various medical fields, emphasizing their promise but noting the need for standardization and clinical testing before widespread application.

This review highlights new perspectives in genomics and epigenomics for skin rejuvenation, comparing innovative strategies like senolytics and DNA repair modulators with classical treatments, and emphasizing the importance of tailoring therapies using individual genomic profiles for personalized anti-ageing approaches.

This study found that the Keyora Lycopene 23 in 1 formulation may improve various aspects of male endocrine and reproductive health by targeting oxidative stress, nitric oxide deficiency, and hormonal imbalance.

In this study, exosomes derived from Iris germanica L. rhizomes (Iris-exosomes) were reported to alleviate oxidative stress and improve mitochondrial function in human follicle dermal papilla cells by activating the Wnt/β-catenin signaling pathway, suggesting potential benefits for hair loss treatment.

This study examined interactions between immune cells and dermal papilla cells in a patient with alopecia areata using single-cell RNA sequencing; it identified specific T cell subtypes and ligand-receptor pairs that may contribute to hair cycle disruption through inflammation.

This study using scRNA-seq on 96 skin biopsies from 51 healthy individuals revealed distinct cell signaling pathways in different skin sites, including unique pathways in facial and palmoplantar skin, which may explain their varying susceptibilities to skin disorders.

This article reviews the potential of nanotechnology, particularly silver nanoparticles, to reduce the toxicity and side effects of cancer drugs, without reporting new clinical results.

This paper reviews the advancements and applications of single-cell transcriptomics in animal research, highlighting its potential to enhance understanding of animal nutrition, health, genetics, and disease models.

This narrative review examines the structure-function relationship in bioactive biopolymers used to promote healing in chronic wounds, emphasizing diabetic ulcers, and underscores the importance of characterizing these biopolymers to enhance their bioactivity for better tissue regeneration outcomes.

This review highlights exosomes as a promising treatment for skin damage from UV light, infrared radiation, burns, and disorders due to their anti-inflammatory properties, ability to induce macrophage polarization, and acceleration of skin repair and regeneration.

This review highlights how organoid technology is transforming precision medicine by summarizing its development and applications in modeling diseases, testing drug efficacy, and tailoring patient-specific treatments, despite current challenges in standardization and ethical considerations.