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Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Aging causes skin stem cells to work less effectively.

AGA linked to inflammation, stress, fibrosis, and disturbed hair follicle stem cells.

The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Hair follicle regeneration and delivery is complex due to many molecular and cellular factors.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Skin stem cells in hair follicles are important for touch sensation.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

EZH2 is essential for hair growth and skin cell development.

Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.

Minoxidil and finasteride effectively treat hair loss.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Mice without collagen VI have slower hair growth normally but faster regrowth after injury.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

The plant extract remedy Satura® Rosta promotes hair growth and regrowth without negative effects.

BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.

Combining CGF and microneedling with betamethasone effectively treats resistant alopecia areata.

A 29-year-old man had a jaw plaque diagnosed as follicular mucinosis, linked to nestin-positive hair follicle stem cells.