Combination Therapy With CGF and Microneedling-Assisted Compound Betamethasone for Resistant Alopecia Areata: A Pilot Study

    September 2024 in “ Journal of Cosmetic Dermatology
    Lingling Jia, Chong Zhao, Hongyi Zhang, Hua Jiang, Jiachao Xiong, Yufei Li
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    TLDR Combining CGF and microneedling with betamethasone effectively treats resistant alopecia areata.
    This pilot study evaluated the effectiveness and safety of combining concentrated growth factor (CGF) with microneedling-assisted compound betamethasone for treating resistant alopecia areata (AA) in seven patients unresponsive to conventional therapies. Results showed that one patient (14.3%) experienced over 50% hair regrowth, while six patients (85.7%) achieved complete recovery without adverse effects. The significant improvement in SALT scores from baseline to the final visit supports the efficacy of this dual treatment approach, suggesting it as a promising and well-tolerated option for refractory AA.
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