Microneedling Combined With Compound Betamethasone in Treatment of Severe Alopecia Areata: A Case Report

August 2022 in “ Frontiers in Immunology ”

Danning Pei, Lirong Chen, Yue Yao, Linxi Zeng, Guo-Qiang Zhang

microneedling compound betamethasone alopecia areata dermoscopic examination betamethasone hair loss dermoscopy

From the encyclopedia

Microneedling →

technique to create small wounds in skin to activate collagen production and hair growth

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Betamethasone →

Studysummary This study reported significant hair regeneration in a 3-year-old with severe alopecia areata after six months of treatment with microneedling and compound betamethasone. Our plain-language summary of this paper — not a Tressless recommendation.

This case report details the treatment of a 3-year-old female with severe alopecia areata using microneedling combined with compound betamethasone. After 6 months of weekly sessions, the patient showed almost complete hair regrowth with no adverse reactions or recurrence. Dermoscopic examination confirmed significant improvement, indicating the potential of this combined treatment as an effective approach for severe alopecia areata. The study underscores the need for further research to validate long-term efficacy and safety.

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Research cited in this study

9 / 9 results

research Microneedling in Androgenetic Alopecia: Comparing Two Different Depths of Microneedles

10 citations , September 2020 in “Journal of Cosmetic Dermatology”

In this study, microneedling with a depth of 0.6 mm, alongside minoxidil, significantly improved hair count and thickness in patients with androgenetic alopecia compared to minoxidil alone, and was more beneficial than a 1.2 mm depth.

Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway

research Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway

10 citations , May 2020 in “Journal of Dermatological Treatment”

This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.

research Ophiasis Alopecia Areata Treated with Microneedling

1 citations , April 2020 in “Baylor University Medical Center Proceedings”

This case report describes a 58-year-old man with ophiasis-pattern alopecia areata who showed significant hair regrowth after treatment with clobetasol and microneedling with triamcinolone.

research Microneedling for the Treatment of Hair Loss

58 citations , December 2017 in “Journal of The European Academy of Dermatology and Venereology”

This review highlights that microneedling shows some promise for improving hair growth in alopecia, particularly when used with other treatments, though more research is needed to establish its efficacy and protocols.

research Alopecia Areata: Successful Outcome with Microneedling and Triamcinolone Acetonide

53 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Microneedling combined with triamcinolone can safely stimulate faster hair regrowth in people with Alopecia Areata.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations , January 2013 in “International Journal of Trichology”

This study found that adding microneedling to minoxidil treatment significantly improved hair growth in men with androgenetic alopecia compared to minoxidil alone across all assessed measures.

Effects of Topical Application of Growth Factors Followed by Microneedle Therapy in Women with Female Pattern Hair Loss: A Pilot Study

research Effects of Topical Application of Growth Factors Followed by Microneedle Therapy in Women with Female Pattern Hair Loss: A Pilot Study

34 citations , October 2012 in “Journal of Dermatology”

This pilot study suggests that using growth factors followed by microneedle therapy may benefit women with female pattern hair loss.

research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012

218 citations , April 2012 in “British Journal of Dermatology”

This updated guideline from the British Association of Dermatologists discusses current recommendations for managing alopecia areata but reports no new clinical research findings.

research Videocapillaroscopic Pattern of Alopecia Areata Before and After Diphenylcyclopropenone Treatment

17 citations , October 2011 in “International Journal of Immunopathology and Pharmacology”

This study found that after 24 weeks of DPCP treatment for alopecia areata, there was a significant increase in new capillaries and hair regrowth detectable by videocapillaroscopy.