Ophiasis Alopecia Areata Treated with Microneedling

April 2020 in “ Baylor University Medical Center Proceedings ”

Usman Asad, Daniel T. Wallis, Michelle Tarbox

ophiasis alopecia areata alopecia areata microneedling clobetasol triamcinolone AA

From the encyclopedia

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Microneedling →

technique to create small wounds in skin to activate collagen production and hair growth

Studysummary This case report describes a 58-year-old man with ophiasis-pattern alopecia areata who showed significant hair regrowth after treatment with clobetasol and microneedling with triamcinolone. Our plain-language summary of this paper — not a Tressless recommendation.

The article discusses a case of a 58-year-old man with ophiasis alopecia areata, a subtype of AA that presents as a band-like hair loss pattern on the occipital, temporal, and parietal regions of the scalp. The patient was treated with clobetasol 0.05% solution and four treatments of microneedling with triamcinolone over 6 months, resulting in gradual improvement, most notably on his left occipital scalp where his hair loss was most prominent, with near complete hair regrowth on his left occipital scalp. Microneedling with triamcinolone can be considered as a promising treatment in cases of ophiasis AA.

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Research cited in this study

5 / 5 results

research Alopecia Areata: A Review of Disease Pathogenesis

191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”

This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.

research Microneedling for the Treatment of Hair Loss

58 citations , December 2017 in “Journal of The European Academy of Dermatology and Venereology”

This review highlights that microneedling shows some promise for improving hair growth in alopecia, particularly when used with other treatments, though more research is needed to establish its efficacy and protocols.

research Successful Treatment of Corticosteroid-Resistant Ophiasis-Type Alopecia Areata with Platelet-Rich Plasma

30 citations , August 2015 in “JAAD case reports”

This case report describes a patient with corticosteroid-resistant ophiasis alopecia areata who experienced prompt hair regrowth after receiving platelet-rich plasma injections.

research Alopecia Areata Update

19 citations , June 2015 in “Seminars in Cutaneous Medicine and Surgery”

This review discusses the clinical presentation, epidemiology, pathophysiology, and treatment options for alopecia areata and reports no new clinical findings.

research Case of Intractable Ophiasis Type of Alopecia Areata Presumably Improved by Fexofenadine

6 citations , May 2012 in “The Journal of Dermatology”

This letter reports on a case of intractable ophiasis-type alopecia areata that was presumably improved by fexofenadine, but no new clinical results are presented.