Microneedling Dilates the Follicular Infundibulum and Increases Transfollicular Absorption of Liposomal Sepia Melanin

    Gabriel Serrano, Patricia Almudever, Juan Monte Serrano, Julio Cortijo, Carmen Faus, Magda Reyes, I. Lopez Exposito, Ana Torrens, Fernando Millán
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    TLDR Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.
    The study from June 2015 demonstrated that microneedling, using an electrical device called the Nanopore turbo roller, significantly enhances the absorption of liposomal sepia melanin into hair follicles. The procedure resulted in a 47% increase in the width of the follicular infundibulum and allowed for greater deposits of melanin at various depths within hair structures compared to manual application. This finding suggests that microneedling could improve the efficacy of laser hair removal, particularly for individuals with lightly pigmented hair, by facilitating deeper and more even distribution of melanin. The document also highlighted the broader applications of microneedling in enhancing skin absorption of various compounds and its potential in improving treatments for conditions like melasma, alopecia areata, and androgenetic alopecia. However, the study's conclusions may be influenced by potential conflicts of interest, as the authors are associated with Sesderma Laboratories. Clinical trials on liposomal melanin lotions for laser hair removal have shown mixed results, but the combination of microneedling with melanin formulations could potentially reduce treatment time and costs.
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      community Can microneedling damage existing hair?

      in Microneedling  9 upvotes 5 days ago
      Microneedling is unlikely to damage existing hair if done with a device using a smaller needle count, like a 9-needle cartridge, and a stamping motion. Hair follicles are deeper than the typical needle penetration depth.

      community I don't know how microneedling works so well but it does.

      in Microneedling  106 upvotes 6 days ago
      Microneedling, combined with finasteride and minoxidil, appears to enhance hair growth, with users reporting noticeable improvements. The process involves using a 0.5mm derma roller, which some believe increases blood flow and stimulates hair follicles.

      community Is microneedling really that effective?

      in Microneedling  33 upvotes 1 week ago
      Microneedling's effectiveness for hair growth is debated, with some users reporting positive results when combined with minoxidil and finasteride, while others experienced scarring and no benefits. Needle depth and frequency vary, with some suggesting 0.5-1mm as effective, but caution is advised to avoid overuse and potential harm.

      community 3mm microneedling with derma-stamp?

      in Microneedling 1 week ago
      The conversation discusses experimenting with microneedling for hair loss, with OP considering using a 3mm derma-stamp. Other users advise against going beyond 1.5mm to avoid damage.

      community Do you keep gains if you stop microneedling?

      in Microneedling  15 upvotes 3 weeks ago
      Stopping microneedling may result in losing hair gains, as it enhances the effectiveness of treatments like minoxidil. Combining microneedling with minoxidil and finasteride is more effective than using microneedling alone.

      community Microneedling and hair transplants - my hair surgeon advised against it

      in Microneedling  7 upvotes 3 weeks ago
      The user started on Finasteride, switched to Dutasteride, and is considering microneedling but was advised against it by their hair surgeon due to potential scalp issues affecting a planned hair transplant. Other users suggest alternatives like Minoxidil, PRP, and avoiding microneedling due to the risk of scar tissue impacting transplant results.

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