Alopecia Secondary to Hyaluronic Acid Injection: A Case Report and Literature Review

This case report highlights a rare instance of filler-induced alopecia in a young woman following hyaluronic acid filler injections, showing successful hair regrowth and scar resolution through multidisciplinary treatment including hyaluronidase and other therapies, emphasizing early recognition and intervention.

This study observed that six sessions of injections using a stabilized hyaluronic acid compound improved hair thickness, shine, density, and reduced hair loss in volunteers with moderate androgenetic alopecia, with excellent treatment tolerability and high satisfaction reported by 88.5% of participants.

In this case study, a patient developed parieto-temporal pain, tissue necrosis, and alopecia after receiving a hyaluronic acid injection for temporal augmentation, which was effectively treated with hyaluronidase and aspirin.

This study reviewed cases of filler-induced alopecia and found that hyaluronic acid injections were most commonly associated with this condition, highlighting that hyaluronidase treatments can rapidly restore hair density, while alternative interventions need further exploration.

This study highlights the significant risk of vascular embolism associated with hyaluronic acid filler injections, emphasizing concerns about potential irreversible damage when fillers are injected in "unexplored" facial areas due to complex and variable facial anatomy.

This case study highlights the rare occurrence of scarring and nonscarring alopecia following vascular occlusion from dermal filler injections, with the researchers suggesting that a combined treatment including hydroxychloroquine might improve outcomes for this complication.

This study reports that percutaneous superficial temporal arterial hyaluronidase injection effectively treated necrosis of the frontotemporal skin and ipsilateral scalp, with patients experiencing significant recovery in skin appearance and hair regrowth 2 to 3 months after injection, following complications from hyaluronic acid filler.

This study found that concentrated growth factor injections significantly improved hair density, hair follicle density, and hair diameter in 60 patients with androgenic alopecia, with a 93% patient satisfaction rate and no reported complications over a 6-month follow-up period.

This article provides information on data availability but reports no new research findings.

This study suggests that hair loss and reduced arterial blood flow after hyaluronic acid filler injection in the temporal region may result from arterial compression rather than intra-arterial occlusion.

This study found that a noncrosslinked hyaluronic acid filler restored cell viability against UVB-induced cytotoxicity and increased VEGF secretion in human dermal papilla cells, suggesting potential for mesotherapy use after further research.

Dermal fillers can cause hair loss, so dermatologists should be aware.

This article reports a case of a 30-year-old woman developing alopecia after a hyaluronic acid injection, with trichoscopic findings described for the first time.

This review discusses the cosmetic and nutricosmetic efficacy of hyaluronic acid for skin rejuvenation and reports that HA formulations show remarkable anti-aging properties.

Accidental injection of hyaluronic acid caused temporary hair loss and skin damage, but treatment restored hair and healed the skin.

This study found that repeated microneedle stimulation in mice promoted hair growth and increased the expression of hair-growth-related genes, suggesting potential therapeutic uses for alopecia.