Alopecia Secondary to Hyaluronic Acid Injection: A Case Report and Literature Review

    June 2025 in “ Clinical Cosmetic and Investigational Dermatology ”
    Lingling Jia, Jiachao Xiong, Changjiang Zhao … Yufei Li
    Studysummary This study presented a case where a 23-year-old woman with alopecia induced by hyaluronic acid injections experienced full hair regrowth using a combination of Concentrated Growth Factor, microneedling, and minoxidil, and also reviewed literature noting variable success rates with other treatments.
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    Research cited in this study 17

    1. Dermal Filler-Induced Alopecia: A Case Report and Literature Review Journal of Cosmetic Dermatology · 2024
    2. Revitalizing Effect on the Scalp After Injection with a Mechanically Stabilized Hyaluronic Acid Complex in Subjects with Androgenetic Alopecia Journal of Clinical Medicine · 2024
    3. Treacherous Territory: Temple Fillers and Tissue Necrosis Skin health and disease · 2024
    4. Fillers Impacting Follicles: The Emerging Complication of Filler-Induced Alopecia International Journal of Dermatology · 2024
    5. Nonscarring Alopecia After Temporal Lifting Technique With Dermal Fillers JAAD case reports · 2023
    6. A Case of Scarring and Nonscarring Alopecia Secondary to Vascular Occlusion with Dermal Filler Clinical and experimental dermatology · 2023
    7. Efficacy of Percutaneous Superficial Temporal Arterial Hyaluronidase Injection for Hyaluronic Acid Filler-Induced Necrosis and Subsequent Alopecia Aesthetic surgery journal · 2022
    8. Clinical Observation and Evaluation of CGF in the Treatment of Androgenic Alopecia Journal of Cosmetic Dermatology · 2022
    9. The Combination of Platelet-Rich Plasma With Botulinum Toxin A in the Treatment of Hyaluronic Acid Embolic Cutaneous Necrosis and Alopecia Dermatologic Therapy · 2022
    10. Temporary Hair Loss After Injection of Hyaluronic Acid Filler Journal of cosmetic dermatology · 2021
    11. In Vitro Hair Growth Promoting Effect of a Noncrosslinked Hyaluronic Acid in Human Dermal Papilla Cells BioMed Research International · 2021
    12. Filler-Induced Alopecia Journal of dermatology · 2019
    13. Alopecia Secondary to Hyaluronic Acid Embolization: Trichoscopic Findings Skin appendage disorders · 2019
    14. Hyaluronic Acid, a Promising Skin Rejuvenating Biomedicine: A Review of Recent Updates and Pre-Clinical and Clinical Investigations on Cosmetic and Nutricosmetic Effects International journal of biological macromolecules · 2018
    15. Reversible Alopecia with Localized Scalp Necrosis After Accidental Embolization of the Parietal Artery with Hyaluronic Acid Aesthetic plastic surgery · 2017
    16. Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model Annals of Dermatology · 2016
    17. Hyaluronic Acid-Induced Alopecia: A Novel Complication Dermatologic Surgery · 2013