This document presents a case report of a 21-year-old female who developed dermal filler-induced alopecia, a rare complication associated with vascular occlusion and tissue ischemia following aesthetic procedures. After receiving 7 mL of hyaluronic acid filler injections in the temples, tear trough, and eyebrow glabella regions, the patient experienced localized skin necrosis and hair loss. Diagnosis was confirmed through trichoscopy, revealing follicular dropout and white dots. Treatment involved hyaluronidase injections, intralesional corticosteroids, topical minoxidil, and CO2 laser therapy, leading to complete hair regrowth and resolution of scarring over a year. The report highlights the importance of early recognition and intervention, with only 16 cases documented, emphasizing the need for awareness and adherence to safe injection practices to prevent such adverse outcomes.
4 citations,
May 2023 in “JAAD case reports” Hyaluronic acid fillers for temporal lifting can cause hair loss without scarring.
April 2023 in “Clinical and experimental dermatology” A new treatment using hydroxychloroquine, hyaluronidase, and steroids may improve hair loss from dermal filler complications.
3 citations,
November 2022 in “Facial plastic surgery & aesthetic medicine” Using ultrasound to guide temple filler injections improves safety and accuracy.
9 citations,
September 2021 in “Journal of cosmetic dermatology” Getting a hyaluronic acid filler can sometimes cause temporary hair loss due to pressure on an artery, not blockage.
6 citations,
June 2019 in “Journal of dermatology” Dermal fillers can cause hair loss, so dermatologists should be aware.
13 citations,
June 2019 in “Case reports in dermatology” Fat injections in the face can cause hair loss.
11 citations,
January 2019 in “Skin appendage disorders” Hyaluronic acid injections can cause hair loss due to blocked blood vessels.
26 citations,
March 2017 in “Aesthetic plastic surgery” Accidental injection of hyaluronic acid caused temporary hair loss and skin damage, but treatment restored hair and healed the skin.
20 citations,
October 2013 in “Dermatologic Surgery”
April 2024 in “International Journal of Dermatology” Filler injections can cause temporary hair loss, but hyaluronidase can help restore hair within a few months.
4 citations,
May 2023 in “JAAD case reports” Hyaluronic acid fillers for temporal lifting can cause hair loss without scarring.
13 citations,
June 2019 in “Case reports in dermatology” Fat injections in the face can cause hair loss.
August 2020 in “Revista de chimie” Nitroglycerin ointment is now used to treat several skin conditions with fewer side effects.
August 2016 in “InTech eBooks” Esthetic surgery complications can include infections, nerve injury, and more; proper evaluation and technique help prevent them.
