Efficacy of Percutaneous Superficial Temporal Arterial Hyaluronidase Injection for Hyaluronic Acid Filler-Induced Necrosis and Subsequent Alopecia
October 2022
in “
Aesthetic surgery journal
”
TLDR Injecting hyaluronidase into the artery is effective for treating skin death and hair loss caused by hyaluronic acid fillers.
The study investigates the effectiveness of percutaneous superficial temporal arterial hyaluronidase (HAase) injections in treating hyaluronic acid (HA) filler-induced necrosis of the frontotemporal skin and/or ipsilateral scalp, which can lead to subsequent alopecia. Five female patients aged 28-46 were treated with HAase injections, resulting in significant improvements in skin necrosis and alopecia. Skin lesions healed almost completely within 15-20 days, and hair regrowth occurred 2-3 months post-treatment. The study concludes that timely HAase injection is effective for managing HA filler-induced vascular complications and can accelerate hair regrowth, although the small sample size and lack of a control group are limitations.
