January 2025 in “ANNALS OF PAKISTAN MEDICAL & ALLIED PROFESSIONALS” This study found that insulin resistance is common among Pakistani women with PCOS and is independently associated with increased hyperandrogenism, as indicated by correlations with testosterone levels and other androgenic measures.
June 2024 in “Kushtia Medical College Journal” This observational study conducted at Kushtia Medical College explored the socio-demographic and clinical profiles of 100 women with PCOS, highlighting that a significant number of these patients experienced infertility, dysmenorrhea, and metabolic abnormalities, suggesting a need for timely therapeutic interventions.
May 2024 in “Scientific Reports” In this study, researchers examined androgen receptor activity in the adult mouse brain and found specific expression in key brain areas, which could inform understanding of cognitive side effects in humans undergoing androgen deprivation therapy for prostate cancer.
This study examined hair mineral and free amino acid components in various diseases and found that when using effect size analysis, specific components related to diabetes and other conditions were identified, suggesting their potential as novel health indicators.
May 2024 in “International Journal of Advanced Academic Studies” This study found that in Iraqi women with PCOS, those taking vitamin E supplements experienced a significant reduction in androgenic symptoms like hair loss, weight gain, and acne, along with lower levels of certain hormones linked to the condition.
This study in diabetic db/db mice found that treatment with the antihypertensive agents minoxidil or nebivolol stimulated elastogenesis and inhibited elastolysis, leading to restored elastic fibers, reduced aortic stiffening, and normalized blood pressure.
April 2024 in “Nepal journal of dermatology, venereology & leprology” This review highlights that vitamin D is increasingly recognized for its roles in skin health, including treatment of psoriasis, potential applications in conditions like atopic dermatitis, and possible prevention of skin malignancies, as observed in various studies linking low levels to autoimmune skin diseases.
This review discusses various management methods for adolescents with PCOS, highlighting lifestyle modifications and pharmaceuticals like metformin and oral contraceptives, but reports no new clinical results; the authors emphasize individualized treatment plans.
February 2024 in “Scientific reports” This study identified four ferroptosis-related genes, SLC40A1, LCN2, CREB5, and SLC7A11, as potential diagnostic markers for alopecia areata, revealing reduced expression in affected patients compared to controls, with a predictive model showing high accuracy in differentiating the condition.
January 2024 in “Frontiers in endocrinology” This study found that women treated with GnRHa for central precocious puberty had a higher prevalence of polycystic ovary syndrome in adulthood compared to those with isolated premature thelarche.
January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study reports that an intervention decreased glucose and insulin levels, indicating improved insulin resistance, which is linked to a skin condition called acne vulgaris and other disorders associated with insulin resistance.
January 2024 in “Pediatria Polska” This study found that long-COVID symptoms in children with multisystem inflammatory syndrome did not differ significantly across SARS-CoV-2 variants, with factors like age being more impactful.
December 2023 in “Pakistan Journal of Medical & Health Sciences” This study found that in South Asian women with PCOS, the severity of non-alcoholic fatty liver disease is strongly linked to early renal dysfunction, as indicated by increased serum creatinine and urinary albumin levels, and reduced eGFR.
October 2023 in “Research Square (Research Square)” In this study, researchers found that patients with new-onset mild alopecia areata had higher levels of oxidative stress markers and reduced antioxidant levels compared to healthy individuals, suggesting that oxidative stress might play a role in the condition.
September 2023 in “Deleted Journal” This study, conducted at the Surgical Outpatient Clinics of the Medical Research Institute in Alexandria, Egypt, found that post-bariatric surgery patients commonly experienced gastrointestinal and dermatological issues, fatigue, impaired physical activity, and psychological conditions like anxiety within the first year after surgery.
January 2023 in “International journal of medical science and health research” This study found that anovulatory PCOS patients were younger, had longer menstrual cycles, and higher systolic blood pressures compared to ovulatory patients.
January 2023 in “Book of Abstracts” COVID-19 can cause different types of hair loss, with telogen effluvium being the most common.
June 2022 in “International journal of drug delivery technology” This study investigated the hair growth-promoting effect of topical nebivolol cream in mice, but the abstract does not provide specific results or conclusions.
June 2022 in “Biomedical reports” This study concluded that STK11 gene polymorphisms were not predictive of metformin response in women with PCOS, though they may influence alopecia and hirsutism.
This study found that resveratrol improved ovarian function, menstrual irregularities, hair loss, and sex hormone levels in patients with polycystic ovary syndrome compared to placebo.
August 2021 in “International Journal of Research in Dermatology” This study observed significant abnormalities in clinical and laboratory parameters related to metabolic syndrome among patients with skin tags.
August 2021 in “Clinical and Experimental Dermatology” This article discusses the introduction of the term 'prepubertal pattern hair loss' to describe hair thinning in children under 10 without physical abnormalities, and reports no new clinical findings.
July 2021 in “Advances in laboratory medicine” This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.
June 2020 in “Journal of Investigative Dermatology” This study of photobiomodulation therapy devices for androgenetic alopecia found variable improvements in hair grade across different skin types and devices, suggesting a need for larger, more comprehensive trials.
In this study, data from the FAERS database indicated varied associations between certain medications and obstructive sleep apnea, with some biologics associated with a decreased risk of developing the condition.
February 2020 in “Scholars academic journal of pharmacy” This case report describes a 78-year-old patient whose orlistat treatment for obesity likely led to hepatotoxicity, which improved after the medication was discontinued.
March 2019 in “Journal of Investigative Dermatology” This review discusses a quiz related to seborrheic dermatitis diagnosis and key findings from a previous study, but reports no new clinical results.
September 2018 in “International journal of biosciences” This study found that women with both PCOS and gingivitis had significantly higher levels of AMH in their saliva compared to those with only PCOS, gingivitis, or neither condition.
January 2018 in “Deleted Journal” In this observational study of 110 women with PCOS, the researchers found that 52.7% experienced depression and anxiety, with Metformin being the most prescribed drug. Regular counseling and lifestyle management were noted to improve the overall disease prognosis.
November 2017 in “Dermatologic Therapy” This study reports that a new topical solution, AB-102, containing a high concentration of a weak α1 agonist, significantly reduces hair shedding during brushing by up to 77% without causing cardiac or hemodynamic adverse events.