TLDR Individualized treatment plans, including lifestyle changes and specific medications, are crucial for managing PCOS in adolescents.
This review examines various management methods for adolescents with polycystic ovarian syndrome (PCOS), highlighting the importance of individualized treatment plans. Lifestyle modifications, such as vigorous exercise and low-carbohydrate diets, are the most preferred methods for symptom reduction. Pharmaceuticals like metformin, oral contraceptives, GnRH antagonists, finasteride, eflornithine, FGFs, and vitamin D show promise in improving insulin sensitivity, regulating menstrual cycles, and reducing hirsutism. Epilatory and surgical options are considered only when other treatments fail and the patient reaches an appropriate age. The review emphasizes the need for personalized pharmacotherapy based on each adolescent's unique symptoms.
68 citations,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
135 citations,
April 2017 in “Advances in Clinical and Experimental Medicine” New treatments for PCOS show promise, including both medication and non-medication options.
4 citations,
January 2017 in “Acta Endocrinologica” Finasteride and metformin both help treat PCOS, but using them together works best.
47 citations,
July 2016 in “Current pharmaceutical design” The document concludes that managing hirsutism in PCOS involves long-term treatment guided by severity, using oral contraceptives and possibly antiandrogens, with attention to individual patient needs.
23 citations,
February 2014 in “Journal of Pediatric and Adolescent Gynecology” Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.
1265 citations,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
14 citations,
February 2016 in “Journal of Obstetrics and Gynaecology Research” Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.
3 citations,
January 2012 in “Hanyang Medical Reviews” The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
10 citations,
November 2010 in “Skin therapy letter” Women with PCOS often have acne because of high androgen levels, and the article reviewed how to treat this type of acne.
85 citations,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
