November 2012 in “International Journal of Data Science and Artificial Intelligence” This study found that the petroleum ether extract of Glycyrrhiza glabra roots promoted faster and longer hair growth in female Wistar rats compared to minoxidil and control treatments.
May 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the potential health benefits of pumpkin seed oil, including heart health and hair growth, but reports no new clinical results.
August 2026 in “International Journal of Innovative Science and Research Technology (IJISRT)” This study investigated the development of a polyherbal cosmeceutical serum containing extracts from five herbal drugs as a potentially safer treatment for alopecia areata, assessing its properties and stability.
1 citations
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December 2007 in “Journal of Microbiology and Biotechnology” This study found that Minoxidil included in triamino alpha-cyclodextrin significantly promoted hair growth in mice, potentially due to its enhanced substantivity on skin.
19 citations
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October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that the MXD/HP-β-CD GEL formulation promoted greater hair growth and improved gene expression related to hair growth in male rats compared to MXD solution or control groups.
September 2024 in “Research Repository Universitas Islam Negeri Maulana Malik Ibrahim (University of Southampton)” In this study, researchers identified an optimal shampoo formulation using Design Expert software, which showed no significant differences in viscosity and foam height, and the physical characteristics met acceptable standards, suggesting its potential for supporting hair health and preventing hair loss.
7 citations
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July 2022 in “Pharmaceuticals” This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.
June 2026 in “International Journal of Drug Delivery Technology” In this study, researchers developed a polyherbal hair growth oil using botanical substances and base oils like coconut and castor oil, finding it to be stable, non-irritating, and suggesting potential hair-growing properties through mechanisms such as scalp blood flow improvement and anti-inflammatory effects.
January 2022 in “Pharmaceutical Sciences Asia” This study found that a liposome containing butterfly pea flower extract and clove oil was stable and, when used by 15 volunteers over 60 days, enhanced eyebrow thickness and darkness without causing irritation.
January 2024 in “Elsevier eBooks” In this chapter, the authors discuss various plant biomass sources, such as Aloe vera and cocoa, highlighting their potential benefits in cosmetics for addressing skin and hair issues like aging, inflammation, and dandruff.
January 2015 in “대한미용학회지” This study found that sandalwood oil significantly increased alkaline phosphatase activity and expression of hair growth-promoting factors in mice, suggesting its potential role in enhancing hair growth markers.
8 citations
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August 2020 in “Domestic Animal Endocrinology” This study found that melatonin treatment improved cashmere production for one cycle in cashmere goats, enhancing fiber quality and follicle activity, but had no effects in the subsequent cycle.
August 2025 in “South African Journal of Botany” This study found that among various polyherbal hair oil formulations using indigenous Bangladeshi plants, Formulation B was most effective, displaying strong antimicrobial activity and promoting hair regrowth in rabbits, surpassing the standard 2% minoxidil treatment, while also being safe for topical use.
52 citations
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January 2020 in “Scientific Reports” This study found that nanostructured lipid carriers with clobetasol propionate significantly enhance follicular drug delivery compared to commercial cream, and manual massage further doubles follicular retention.
1 citations
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February 2005 in “OakTrust (Texas A&M University Libraries)” In this study, dogs fed Diet B with specific levels of dietary zinc and linoleic acid showed improved skin and hair coat conditions, evidenced by increased hair follicle growth and higher skin lipid scores.
December 2025 in “International Journal of Pharmaceutical Sciences Review and Research” In this study, a newly developed polyherbal hair oil exhibited promising characteristics, including a beneficial pH and antimicrobial activity against Staphylococcus aureus, with preliminary tests suggesting it supports scalp and hair health without adverse effects.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study used a multi-layer in silico framework to evaluate Korean herbal compounds for androgenetic alopecia, identifying Biochanin A, Saponin Re, and Emodin as potential topical candidates with distinct safety and affinity profiles, although these findings remain purely computational without experimental validation.
31 citations
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September 2009 in “Natural Product Research” In this study, petroleum ether extract of Citrullus colocynthis fruit effectively promoted hair growth in a mouse model of androgen-induced alopecia, showing comparable results to the standard treatment, finasteride.
46 citations
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March 2009 in “Die Pharmazie” This study describes the development of nanostructured lipid carriers for minoxidil as a potential alternative to conventional topical solutions, showing promise for use in topical formulations.
August 2025 in “JOURNAL OF EXPERIMENTAL ZOOLOGY INDIA” This study reported that a spray containing Origanum marjoram essential oil significantly improved hair regrowth, dermal thickness, weight, and lymphocyte levels in rabbits with cyclophosphamide-induced alopecia, suggesting its potential as a natural alternative for hair loss treatment.
11 citations
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December 2011 in “Revista Brasileira de Farmacognosia” In this animal study, petroleum ether and ethanolic extracts of Abrus precatorius seeds appeared to reverse androgen-induced alopecia in male albino rats by inhibiting the 5α-reductase enzyme, similar to finasteride.
19 citations
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July 1993 in “Journal of Applied Toxicology” This study found that various petroleum distillates caused significant skin changes in mice, with severity varying based on the product and penetration pathway, potentially leading to skin tumors through non-genotoxic mechanisms in longer-term exposure.
1 citations
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March 2023 in “PubMed” In this research, a 1% rosemary extract hair lotion was found to promote hair growth in mice more effectively than a standard minoxidil treatment.
4 citations
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June 2016 in “Journal of Pharmacopuncture” This study found that Cornu cervi pantotrichum pharmacopuncture solution significantly promoted hair growth in mice by enhancing hair follicular cell proliferation and up-regulating FGF-7 expression.
May 2025 in “Journal of Dispersion Science and Technology” This study reported that a novel SMEDDS formulation of PPO demonstrated better permeation and improved hair growth compared to a marketed formulation in tests for managing androgenetic alopecia, with further exploration suggested.
This study found that niosomal aminexil was more clinically effective for hair growth than conventional aminexil solutions, and that niosomes facilitated aminexil penetration through rat skin without propylene glycol.
In this study, 20% whale oil applied to mice was observed to promote hair growth more effectively than a control or 3% minoxidil, showing increased hair follicles and thicker subcutaneous tissue.
2 citations
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November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
January 2026 in “Revista Científica de la Facultad de Ciencias Veterinarias” This study concluded that both ozonated oil and Centella asiatica extract effectively accelerated wound healing in mice through different mechanisms, with the former enhancing early-stage inflammation and the latter promoting collagen deposition and regenerative healing.
January 2026 in “Buletin Veteriner Udayana” This study documented a case of Dipylidium caninum infection in a 4-month-old female dog, effectively treated with a deworming medication, resulting in significant improvement and no worms detected after five days. Routine deworming and maintaining hygienic conditions are recommended to prevent reinfection and transmission.