7 citations,
July 2018 in “International Journal of Applied Pharmaceutics” Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
July 2022 in “http://isrctn.com/” Adding a cosmetic gel with caffeine, taurine, and growth factors to standard hair loss treatments could improve results.
September 2014 in “Hair transplant forum international” Caffeine, niacinamide, and panthenol may improve hair growth, fullness, and healing when applied to the scalp.
61 citations,
May 2014 in “International journal of pharmaceutics” Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
42 citations,
July 2014 in “European journal of pharmaceutics and biopharmaceutics” Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.
10 citations,
July 2021 in “European journal of pharmaceutics and biopharmaceutics” Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
5 citations,
January 2020 in “Journal of Dermatology and Dermatologic Surgery” Caffeine may benefit skin and hair health but more research is needed to confirm its effectiveness in dermatology.
August 2024 in “Cosmetics” Caffeine is beneficial for skin and hair treatments but needs better delivery methods to penetrate deeper skin layers.
182 citations,
December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
1 citations,
July 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” Topical caffeine improves hair loss intensity, speed, and shedding, and works better with minoxidil/azelaic acid.
September 2023 in “Authorea (Authorea)” Certain peptides, caffeine, taurine, and an iron complex may improve hair regrowth when used with minoxidil and finasteride for hair loss.
The optimal concentration for caffeine release in gel form is 0.2% caffeine and 2.3% chitosan.
40 citations,
August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
21 citations,
November 2012 in “Plastic and Reconstructive Surgery” Both genetic and lifestyle factors significantly affect female hair loss.
September 2022 in “Polish Hyperbaric Research” Some treatments for hair loss, like finasteride, biotin, and minoxidil, can be effective, but their success varies by individual case.
35 citations,
January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
21 citations,
January 2017 in “Skin Pharmacology and Physiology” Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.
6 citations,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
67 citations,
November 2019 in “Molecules” Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.
15 citations,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
1 citations,
May 2021 in “Journal of Cosmetic Dermatology” Cosmetic foam product reduces hair loss and increases hair density in men.
Arabica coffee pulp extract may help prevent hair loss and promote hair growth.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” Caffeine intake during pregnancy and lactation can cause skin lesions in mother rats and their babies, not linked to cortisol levels.
46 citations,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
29 citations,
December 2011 in “British Journal of Dermatology” A new hair treatment with caffeine and other ingredients makes hair thicker and less likely to break.
8 citations,
June 2022 in “Cosmetics” Coffee berry extract may help slow skin aging and prevent hair loss.
12 citations,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
8 citations,
April 2020 in “European Journal of Nutrition” Newborns' hair shows how much caffeine their mothers drank during pregnancy.
31 citations,
February 2019 in “International Journal of Cosmetic Science” Caffeine applied to the scalp can protect hair follicles from UV damage.
November 2023 in “Hair transplant forum international” Caffeine can stimulate hair growth, but the best dose and frequency for hair loss treatment are still unknown.