research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
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330-360 / 970 resultsresearch Anabolic Effects of Testosterone Are Preserved During Inhibition of 5α-Reductase
Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
research Male Pattern Baldness and Prostate Cancer Risk in a Population-Based Case-Control Study
Men who start losing hair at age 30 may have a lower risk of prostate cancer.
research Phytochemicals With Anti 5-Alpha-Reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.
research Oral Presentations: Abstracts of the Urological Society of Australia and New Zealand Annual Scientific Meeting, Melbourne, Australia
Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.
research Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride
Food intake, not genetics, affects how the body processes tadalafil and finasteride.
research Addressing Androgenetic Alopecia: A Complex Disorder with a Multilateral Treatment Strategy
Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
research Androgenetic Alopecia: An Update
Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
research Isolation and HPLC Quantitative Determination of 5α-Reductase Inhibitors from Tectona Grandis Leaf Extract
Teak leaf extract contains compounds that could help treat hair loss.
research Stauntonia Hexaphylla Extract Ameliorates Androgenic Alopecia by Inhibiting Androgen Signaling in Testosterone-Induced Alopecia Mice
Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System
Cannabinoids may help treat various skin conditions.
research Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases
Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects
GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
research Clinical Biochemistry of Dihydrotestosterone
Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
research Biological Activities of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments
THSG from a Chinese plant helps with aging and related diseases.
research Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial
Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.
research Direct Vasodilators and Sympatholytic Agents
Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
research Adipokines in the Skin and Dermatological Diseases
Adipokines affect skin health and could be targeted for treating skin diseases.
research The Double-Edged Sword of Testosterone’s Role in the COVID-19 Pandemic
Testosterone may influence COVID-19 severity and outcomes.
research Stem Cell Therapy for Burns: The Story So Far
Stem cell therapy shows promise in improving burn wound healing.
research EZH2-Mediated Inhibition of MicroRNA-22 Promotes Differentiation of Hair Follicle Stem Cells by Elevating STK40 Expression
The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway
research PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair
PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
research Repigmentation by Combined Narrow-Band Ultraviolet B/Adipose-Derived Stem Cell Transplantation in the Mouse Model: Role of Nrf2/HO-1-Mediated Ca2+ Homeostasis
Combining narrow-band ultraviolet B light and stem cell transplantation helps repigmentation in vitiligo by maintaining calcium balance in mice.
research Broussonetia Papyrifera Promotes Hair Growth Through the Regulation of β-Catenin and STAT6 Target Proteins: A Phototrichogram Analysis of Clinical Samples
Broussonetia papyrifera extract helps hair growth by regulating specific proteins.
research The Post-Finasteride Syndrome: Possible Etiological Mechanisms and Symptoms
Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
research The Use of Natural Ingredients in the Treatment of Alopecias with an Emphasis on Central Centrifugal Cicatricial Alopecia: A Systematic Review
Some natural ingredients like onion juice, rosemary oil, and pumpkin seed oil may help with hair growth and reducing hair loss.
research Skin Applications of Cannabidiol: Sources, Effects, Delivery Systems, Marketed Formulations and Safety
CBD may improve skin and hair health, but its effective use and safety need more research.