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Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

A woman with anorexia and Cushing's syndrome improved after tumor removal, highlighting the need to consider hormonal issues in psychiatric conditions.

Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.

Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

A new gene variant causes glucocorticoid resistance in a mother and son.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.