Anthropometric Characteristics of Polycystic Ovary Syndrome and Their Associations with Insulin Resistance and Lipid Profile

This study investigated the body composition differences between women with PCOS and those without, using anthropometric methods, and examined their potential as predictors of insulin resistance (IR) and lipid profile (LP). The study included 126 women with PCOS and 159 controls. Women with PCOS exhibited higher body mass index, fat mass percentage, and testosterone levels. Fat mass was linked to higher triglycerides and LDL-c, and lower HDL-c, regardless of PCOS status. HOMA-IR was more significant in PCOS patients and related to fat mass. Higher bone mass correlated with lower cholesterol levels, independent of PCOS. Lean mass predicted a better metabolic profile, influenced by PCOS. The study emphasized the role of body composition in PCOS and its association with a poorer metabolic profile, with PCOS linked to worse HOMA-IR independent of body composition.