TLDR Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
The study investigated bone mineral density (BMD) in 60 young women with polycystic ovary syndrome (PCOS) compared to 58 healthy controls, using dual-energy X-ray absorptiometry for measurement. Results indicated no significant difference in BMD between the PCOS group and controls. However, obese women with PCOS had significantly higher BMD at certain sites compared to overweight and lean women with PCOS. BMD was found to positively correlate with BMI, but not with insulin resistance or serum testosterone levels. The study concluded that BMI is a key determinant of BMD in women with PCOS, and that BMD does not differ between young women with PCOS and healthy controls. Limitations included a small sample size and the lack of certain assessments, suggesting the need for further research on peak bone mass in women with PCOS across different age groups.
16 citations
,
February 2016 in “Gynecological Endocrinology” Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.
11 citations
,
July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
21 citations
,
August 2014 in “Gynecological Endocrinology” Higher hs-CRP levels in Indian adolescent women with PCOS are more related to BMI than PCOS itself.
22 citations
,
January 2014 in “Indian Journal of Endocrinology and Metabolism” Family members of North Indian women with PCOS have a high rate of metabolic syndrome.
502 citations
,
February 2008 in “The Journal of Clinical Endocrinology & Metabolism” Treat significant hirsutism with medication and hair removal; use birth control pills first, adding antiandrogens if needed.
4809 citations
,
January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
32 citations
,
January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
