Polycystic Ovary Syndrome: A Comprehensive Overview

    January 2019 in “ ISGE series ”
    Stavroula A. Paschou, Dimitrios G. Goulis, Basil C. Tarlatzis
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    TLDR The document concludes that effectively managing PCOS requires a multifaceted approach.
    The 2019 document describes Polycystic Ovary Syndrome (PCOS) as a prevalent endocrine disorder among women of reproductive age, with symptoms including menstrual irregularities, hirsutism, acne, and infertility. It notes the complex pathophysiology of PCOS, involving genetic and environmental factors, and the association with insulin resistance, obesity, and increased risks of metabolic and cardiovascular diseases. The prevalence of PCOS is reported to be between 6% and 20%, depending on the diagnostic criteria. The document stresses the necessity of a comprehensive diagnostic approach, which includes clinical assessment, laboratory tests, and the exclusion of other androgen excess disorders. Treatment is personalized, with lifestyle changes, metformin, oral contraceptive pills, antiandrogens, and fertility treatments being highlighted. The document concludes by emphasizing the importance of a multifaceted approach to manage the various aspects of PCOS effectively.
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