TLDR Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.
The study conducted between September 2014 and May 2016 with 126 women diagnosed with polycystic ovary syndrome (PCOS) and 159 control subjects found that women with PCOS had significantly longer anogenital distances (AGD), particularly the distance from the anterior clitoral surface to the upper verge of the anus (AGDAC), even after adjusting for body mass index (BMI), age, and episiotomy. Women in the upper tertile of AGDAC measurements were 2.9 times more likely to have PCOS. These results suggest that longer AGD may be a biomarker for PCOS, potentially due to the influence of the intrauterine hormonal environment on the development of PCOS. However, the study did not find significant associations between AGD and reproductive hormone levels or antral follicle count. Despite its limitations, such as the potential for chance findings and the inability to establish causality, the study provides initial evidence that prenatal androgen exposure may be linked to PCOS in adulthood.
467 citations,
October 2014 in “European Journal of Endocrinology” The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
352 citations,
January 2006 in “The Journal of Clinical Endocrinology and Metabolism” Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.
4025 citations,
December 2003 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
32 citations,
February 2017 in “Human Reproduction” Women with polycystic ovary syndrome tend to have a longer anogenital distance.
January 2020 in “Proyecto de investigación:” Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.
15 citations,
October 2018 in “Reproductive Biomedicine Online” Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.
1 citations,
January 2023 in “Metabolites” Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
1 citations,
October 2017 in “Elsevier eBooks” Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
