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The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Sebocytes play a key role in controlling androgen levels in human skin.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Nerves and chemicals in the body can affect hair growth and loss.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.