Cutaneous Manifestations of Lupus Erythematosus

    January 2012 in “ Springer eBooks ”
    Henry B. Townsend, Ruth Ann Vleugels
    Image of study
    TLDR Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.
    The document from 2012 outlines the various skin manifestations of Lupus Erythematosus (LE), including LE-specific and LE-nonspecific conditions. It notes that skin symptoms are present initially in 25% of systemic lupus erythematosus (SLE) patients and eventually in 70-80%. The most common form of cutaneous lupus is discoid LE (DLE), which can cause permanent alopecia if it affects the scalp. The document also covers treatment options, emphasizing the importance of smoking cessation, photoprotection, and vitamin D supplementation due to the high photosensitivity of CLE patients. Topical corticosteroids, antimalarials, and other systemic therapies are discussed, with a study of 30 patients showing significant benefit from tacrolimus ointment over placebo. Thalidomide has shown considerable efficacy in a retrospective study of 48 patients, despite its serious side effects. Other treatments like dapsone, retinoids, and biologics have also been effective in various studies, with a Brazilian study of 65 patients reporting a 97% remission rate with thalidomide. The document highlights the need for individualized treatment plans and monitoring due to the potential side effects of these therapies.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 17 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

      in Treatment  7 upvotes 4 years ago
      Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

      community Finasteride not working isnt it MPB?

      in Finasteride/Dutasteride  5 upvotes 6 months ago
      A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

    Related Research

    2 / 2 results