1 citations
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December 2021 in “Annals of phytomedicine” This study found that a herbal hair dye formulated with a 1:2 ratio of henna and indigo successfully colored unpigmented hair dark brown to black, with favorable attributes compared to synthetic dyes.
1 citations
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November 2021 in “Jurnal Farmasi Indonesia” In this study, three hair tonic formulas containing Kayu Secang extracts demonstrated hair growth activity in rabbits, with the chloroform-methanol fraction showing the most significant results.
May 2025 in “Indian Journal of Pharmacology” In this study, researchers reported that standardized rosemary and capsicum extracts significantly improved hair growth parameters such as follicle density, length, and diameter in rats with testosterone-induced alopecia, suggesting these extracts may aid in more effective natural treatments for androgenetic alopecia.
25 citations
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January 2013 in “Journal of Industrial and Engineering Chemistry” This study found that cubosomal suspensions significantly enhanced the hair growth-promoting effects of Thuja orientalis, Polygonum multiflorum Thunberg, and Espinosilla extracts in a mouse model, making them as effective as Minoxidil.
January 2010 in “대한미용학회지” This study found that extracts from Angelica gigas Nakai and Glycyrrhiza uralensis stimulated hair regrowth and follicle development in a shaving mouse model, suggesting potential for hair growth or hair loss prevention in humans.
June 2025 in “Current Trends in Biotechnology and Pharmacy” This study found that when applied for 24 hours, a polyherbal formulation made from Ficus religiosa and Abrus precatorious promoted more significant hair growth in Male Wistar rats than Minoxidil and the control group, and the extracts also exhibited notable antibacterial activities.
July 2022 in “Asian Journal of Biochemistry, Genetics and Molecular Biology” This study found that Ageratum conyzoides showed antihyperglycemic and antilipidemic effects in diabetic rats, with significant changes in hematological and serum electrolyte parameters at 2000mg/kg.
In this study, the combination of binahong leaf and lemongrass extracts was found to effectively inhibit the growth of the dandruff-causing fungus Pityrosporum ovale, with the strongest fungal growth inhibition observed at a 50% concentration of each extract.
March 2018 in “Farmacevtičnij časopis” In this study, researchers developed an optimized production process for the herbal tincture "Stimufit," intended for topical use in treating telogen alopecia, using 40% ethanol and a specific extraction method.
3 citations
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July 2015 in “International journal of pharmacology” In this study, Natural Plant Extracts (NPE) promoted hair growth in mice by stimulating anagen growth and upregulating relevant gene expression, compared to controls with saline.
May 2026 in “Medical and Veterinary Entomology” This study found that the combination of L. sericata secretions and A. sintenisii extract significantly enhanced wound healing compared to each agent alone or Furacin®, suggesting a synergistic effect.
1 citations
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January 2002 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study found that several natural extracts, including Polygonum multiflorum Thunb and Terminalia chebula Retz., promoted hair growth in mouse models but showed limited effectiveness on human hair growth in vitro.
8 citations
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January 2014 in “BioMed Research International” This study reported that among three plant extracts tested for hair growth on nude mice, Eclipta alba significantly increased hair density and length, unlike Asiasari radix and Panax ginseng.
May 2019 in “Eurasian Journal of Biosciences” In this study, researchers observed that fenugreek aqueous extract was more effective than its alcohol extract in inhibiting the growth of bacteria associated with acne, particularly gram-positive bacteria like Staphylococcus epidermidis and Staphylococcus aureus.
2 citations
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October 2024 in “Pharmaceutics” This study found that reducing the particle size of Tetrastigma hemsleyanum powders improved both dissolution rates and antioxidant activity, suggesting potential benefits for enhancing hepatoprotective effects.
June 2026 in “International Journal of Drug Delivery Technology” In this study using fertilized chicken eggs, researchers reported that ethanol and aqueous extracts of clove, cinnamon, and coriander significantly reduced blood vessel formation, indicating these herbs' potential as safe anti-angiogenic treatments without severe side effects compared to synthetic drugs.
January 2021 in “The Korea Journal of Herbology” This study suggests that Achyranthis Radix ethanol extract may promote hair growth by increasing cell proliferation and protein expression in human hair dermal papilla cells.
December 2025 in “Bioscientist Jurnal Ilmiah Biologi” In this study, researchers developed an optimized formulation of a traditional ethnomedicinal recipe from East Nusa Tenggara, which demonstrated strong antioxidant activity and significantly enhanced hair growth in a mouse alopecia model, compared to control groups.
January 2013 in “The Thai Journal of Pharmaceutical Sciences” 16 citations
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September 2022 in “International Journal of Molecular Sciences” This study reported that Juniperus sabina needle extract showed significant anti-butyrylcholinesterase activity, suggesting potential medicinal value due to high podophyllotoxin levels.
24 citations
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December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
January 2024 in “Journal of applied biological chemistry” This study found that Glehnia littoralis and Andrographis paniculata may support hair growth by protecting against oxidative stress and increasing VEGF and Wnt/β-catenin signaling in human hair follicle dermal papilla cells, with enhanced effects when combined.
2 citations
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July 2019 in “International Journal of Neuroscience and Behavioral Science” This study found that ethanol extract of Thevetia peruviana bark demonstrated significant antinociceptive activity in mice, suggesting potential for developing new analgesic drugs.
1 citations
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March 2022 in “Daehanhanuihakoeji” In this study, Artemisia sieversiana extract was found to safely promote hair follicle dermal papilla cell growth and inhibit hair loss through anti-androgen, anti-inflammatory, and antioxidant effects at a cellular level.
7 citations
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August 2020 in “Majalah Farmasetika” This review concluded that a herbal hair tonic formulated with 2.5% green tea leaf extract, in combination with specific solvents and additives, showed the best properties for stimulating hair growth.
2 citations
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August 2016 in “Journal of Investigative Dermatology”
April 2019 in “International research journal of pharmacy” This study found that a 50% ethanolic extract of Adiantum capillus had significant analgesic and anti-inflammatory effects in animals, particularly at the highest tested dose of 300 mg/kg.
North American ginseng extract helped regrow hair in balding mice.
This literature review suggests that Cyperus rotundus L extract is a promising natural agent for promoting hair growth due to its bioactive compounds and mechanisms of action, but emphasizes the need for further human clinical trials to confirm its safety and effectiveness.
June 2026 in “Korean Journal of Food Science and Technology” In this study, a 10% fermented Glycine max compound was found to promote faster hair growth and follicle formation in mice compared to 3% minoxidil, suggesting potential as a hair health supplement.