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The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

MOF controls skin development by regulating genes for mitochondria and cilia.

Understanding where cancer cells come from helps create better prevention and treatment methods.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Stem cell self-renewal is complex and needs more research for full understanding.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.