In this study, researchers found that aloe vera hair tonic preparations containing 10% and 15% extract concentrations significantly enhanced hair growth in rats and remained physically stable across various temperature conditions.
1 citations
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June 2018 in “Pharmaciana” In this study, researchers developed a hair tonic using 7.5% Aloe vera extract and 2.5% licorice extract, finding that the formula with 15% ethanol showed optimum activity by promoting hair growth and increased hair weight in rabbits over 28 days.
June 2024 in “International journal of molecular sciences” In this study, researchers found that topical treatment with adenosine improved hair growth and thickness by significantly increasing hair density and thickness after four months in vivo, with results comparable to minoxidil, potentially due to adenosine's anti-androgenic effects.
In this study, a hair tonic formulation with bean leaf juice increased hair growth in male rabbits, with concentration-dependent improvements in hair length and weight compared to a control.
March 2024 in “Jurnal Tata Rias” This study reported that a ginger-based hair tonic significantly reduced hair loss and improved hair thickness and quality over a two-week period among female participants with hair loss concerns, compared to a control group using other commercial hair loss products.
1 citations
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January 2014 in “Jurnal Tata Rias” In this study, the hair tonic with a 3:3 avocado extract to honey ratio was most preferred by panelists and may be suitable for preventing hair loss.
7 citations
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August 2020 in “Majalah Farmasetika” This review concluded that a herbal hair tonic formulated with 2.5% green tea leaf extract, in combination with specific solvents and additives, showed the best properties for stimulating hair growth.
April 2025 in “International Journal for Research in Applied Science and Engineering Technology” This study developed and tested a herbal hair growth tonic using medicinal plant extracts on animal models, reporting higher anagen/telogen ratio, follicular density, and hair length compared to controls, suggesting it as a potential natural alternative to synthetic products.
This study found that Avicennia marina extract significantly increased hair growth in androgenic alopecia patients, suggesting its potential effectiveness by inhibiting 5 alpha-reductase and regulating relevant growth factors.
10 citations
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October 2015 in “Journal of Dermatology” This study found that adenosine significantly increased the proportion of thick hair in Caucasian men with androgenetic alopecia, with no reported adverse effects.
March 2023 in “Jurnal Ilmiah Medicamento” In this study, herbal hair tonic made from Usada Bali ingredients significantly increased hair growth in mice without causing skin irritation compared to a negative control.
October 2020 in “Journal of bio innovation” In this study, DanEra, an herbal hair tonic from Pomegranate and Beetroot extracts, showed equivalent effectiveness to the standard drug Ketoconazole in microbiological tests and provided significant relief from severe dandruff in all volunteers within 10 days.
1 citations
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July 2022 in “Bandung Conference Series. Pharmacy” This study found that a hair tonic formulation using candlenut oil as an active ingredient could significantly promote hair growth in rabbits, achieving 29.77 mm in 22 days.
11 citations
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April 2015 in “International Journal of Cosmetic Science” This study found that topical adenosine significantly increased the ratio of thick hairs and contributed to global improvement in Japanese men with androgenetic alopecia compared to niacinamide, with no observed adverse events.
This study found that a combination of topical and oral treatment led to greater improvements in hair density, thickness, and anagen/telogen ratio in patients with androgenetic alopecia compared to topical treatment alone, with significant benefits observed over a 3-month period.
1 citations
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June 2022 in “INDIAN JOURNAL OF APPLIED RESEARCH” This review compiles existing knowledge on ashwagandha's potential to stimulate hair growth but reports no new experimental findings, emphasizing its medicinal properties and usage in Ayurvedic medicine.
January 2019 in “Journal of Clinical Dermatology” This study found that a hair tonic containing a human umbilical cord blood mesenchymal stem cell-derived conditioned medium significantly increased hair density, thickness, and growth rate in patients with androgenetic alopecia.
December 2024 in “Medical alphabet” In this study, 20 patients with telogen alopecia showed reduced hair loss and improved hair quality after 9 weeks of treatment with the topical product "Time to Grow" and the dietary supplement "Thick and Strong Hair.
This abstract highlights that maintaining healthy, voluminous thin hair involves using gentle care products, such as shampoos, conditioners, and masks containing specific ingredients like hydrolyzed keratin, collagen, and panthenol, to improve manageability, strength, and moisture retention.
December 2024 in “Biomedical & Pharmacology Journal” In this study, researchers developed and assessed two polyherbal hair tonic formulations, finding that Hair Tonic A containing 10% white tea extract improved hair thickness, manageability, and anti-frizz properties, particularly for blonde and black hair, while demonstrating greater stability compared to Hair Tonic B.
29 citations
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December 2011 in “British Journal of Dermatology” The researchers reported that a novel leave-on treatment containing caffeine, niacinamide, panthenol, dimethicone, and an acrylate polymer significantly increased the diameter and improved the mechanical properties of scalp hair fibers, suggesting it may help mitigate thinning hair.
July 2018 in “Media Informasi” This study found that a 3:2 combination of pandan leaf and mother-in-law's tongue extracts in hair tonic showed similar hair growth activity as 5% minoxidil after three weeks.
1 citations
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December 2018 in “JURNAL PENDIDIKAN DAN KELUARGA” This study found that using senseviera hair tonic significantly increased hair density among women aged 19-25 who wear hijabs.
January 2016 in “Jurnal Farmasi Indonesia” In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.
5 citations
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July 2022 in “International Journal of Health Sciences” In this study, researchers formulated a hair tonic using various herbal extracts and reported effective antifungal and antibacterial properties, along with good consistency, spreadability, homogeneity, appearance, and pH balance.
33 citations
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December 2008 in “Journal of Dermatology” This study found that 0.75% adenosine lotion significantly improved hair growth and thickness in Japanese women with female pattern hair loss compared to a placebo.
October 2024 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study found that the F6 formulation of a hair tonic containing EDS and ATG extracts produced the most significant hair growth in rabbits, without causing skin irritation and remaining stable throughout the observation period.
April 2025 in “Mutiara Jurnal Penelitian dan Karya Ilmiah” In this study of Beauty and Aesthetics students, researchers found that using a hair tonic made from Green Spinach Leaves significantly reduced hair loss when applied weekly, compared to a control, but no significant difference was observed when increasing application to twice weekly.
January 2026 in “Dermatologic Therapy” This study found that a hair serum containing Acanthus ebracteatus extract improved hair regrowth in men with androgenic alopecia, increasing hair count and density of anagen hairs over a 6-month period, with combination treatments showing early effectiveness.
June 2022 in “Jurnal Health Sains” This review discusses plant-based alternatives for hair tonic formulations to address hair loss and contains no new clinical results, advocating for plant extracts as safer options than synthetic ingredients.