Topical Adenosine Increases Thick Hair Ratio in Japanese Men with Androgenetic Alopecia

April 2015 in “ International Journal of Cosmetic Science ”

Y. Watanabe, Toshio Nagashima, Nobutomo Hanzawa, A. Ishino, Yasuhiro Nakazawa, Masashi Ogo, Takashi Iwabuchi, Michio Tajima

topical adenosine androgenetic alopecia AGA niacinamide adenosine

From the encyclopedia

Niacinamide →

Adenosine →

nucleoside used for hair regrowth stimulant properties

Studysummary This study found that topical adenosine significantly increased the ratio of thick hairs and contributed to global improvement in Japanese men with androgenetic alopecia compared to niacinamide, with no observed adverse events. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated the efficacy and safety of topical adenosine in promoting hair growth in Japanese men with androgenetic alopecia (AGA). A total of 104 male volunteers with AGA participated in the study, and they were randomized into two groups. The study was conducted for six months, and the subjects applied either 0.75% adenosine or 0.1% niacinamide to the scalp vertex twice daily. The results showed that adenosine increased the ratio of thick hair in Japanese men with AGA, and it was safe to use. The study suggests that adenosine could be a potential treatment for AGA.

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Research cited in this study

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